2WQ9
Crystal Structure of RBP4 bound to Oleic Acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001523 | biological_process | retinoid metabolic process |
| A | 0001654 | biological_process | eye development |
| A | 0002639 | biological_process | positive regulation of immunoglobulin production |
| A | 0005501 | molecular_function | retinoid binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0007507 | biological_process | heart development |
| A | 0009410 | biological_process | response to xenobiotic stimulus |
| A | 0014850 | biological_process | response to muscle activity |
| A | 0019841 | molecular_function | retinol binding |
| A | 0030277 | biological_process | maintenance of gastrointestinal epithelium |
| A | 0030324 | biological_process | lung development |
| A | 0032024 | biological_process | positive regulation of insulin secretion |
| A | 0032526 | biological_process | response to retinoic acid |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0034632 | molecular_function | retinol transmembrane transporter activity |
| A | 0034633 | biological_process | retinol transport |
| A | 0042572 | biological_process | retinol metabolic process |
| A | 0042593 | biological_process | glucose homeostasis |
| A | 0044877 | molecular_function | protein-containing complex binding |
| A | 0045471 | biological_process | response to ethanol |
| A | 0048562 | biological_process | embryonic organ morphogenesis |
| A | 0048706 | biological_process | embryonic skeletal system development |
| A | 0048738 | biological_process | cardiac muscle tissue development |
| A | 0048807 | biological_process | female genitalia morphogenesis |
| A | 0060044 | biological_process | negative regulation of cardiac muscle cell proliferation |
| A | 0060059 | biological_process | embryonic retina morphogenesis in camera-type eye |
| A | 0060065 | biological_process | uterus development |
| A | 0060068 | biological_process | vagina development |
| A | 0060157 | biological_process | urinary bladder development |
| A | 0060347 | biological_process | heart trabecula formation |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0140104 | molecular_function | molecular carrier activity |
| A | 1904768 | molecular_function | all-trans-retinol binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1175 |
| Chain | Residue |
| A | SER7 |
| A | ARG153 |
| A | ALA162 |
| A | ARG163 |
| A | HOH2182 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1174 |
| Chain | Residue |
| A | LEU123 |
| A | HOH2204 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 1176 |
| Chain | Residue |
| A | ASP79 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1177 |
| Chain | Residue |
| A | VAL47 |
| A | SER46 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1178 |
| Chain | Residue |
| A | LYS150 |
| A | ARG153 |
| A | HOH2204 |
| A | HOH2205 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE OLA A 1179 |
| Chain | Residue |
| A | LYS29 |
| A | PRO32 |
| A | LEU35 |
| A | PHE36 |
| A | LEU37 |
| A | PHE45 |
| A | ALA55 |
| A | VAL74 |
| A | GLY75 |
| A | TYR90 |
| A | HIS104 |
| A | GLN117 |
| A | PHE135 |
| A | PHE137 |
| A | HOH2226 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 1180 |
| Chain | Residue |
| A | ARG10 |
| A | VAL11 |
| A | LYS12 |
| A | VAL107 |
| A | ASP108 |
| A | ARG155 |
| A | GLU158 |
| A | HOH2206 |
| A | HOH2208 |
| A | HOH2227 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1181 |
| Chain | Residue |
| A | GLY22 |
| A | THR23 |
| A | GLU44 |
| A | ARG139 |
| A | HOH2228 |
| A | HOH2229 |
| A | HOH2230 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 1182 |
| Chain | Residue |
| A | LYS29 |
| A | LYS30 |
| A | ASP31 |
| A | GLN164 |
| A | ARG166 |
| A | HOH2073 |
| A | HOH2216 |
| A | HOH2231 |
| A | HOH2232 |
| A | HOH2233 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. NFDkaRFSGTWYAM |
| Chain | Residue | Details |
| A | ASN14-MET27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P27485","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"UniProtKB","id":"Q00724","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
