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2WOJ

ADP-AlF4 complex of S. cerevisiae GET3

Functional Information from GO Data
ChainGOidnamespacecontents
A0000750biological_processpheromone-dependent signal transduction involved in conjugation with cellular fusion
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0006457biological_processprotein folding
A0006620biological_processpost-translational protein targeting to endoplasmic reticulum membrane
A0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A0008270molecular_functionzinc ion binding
A0009408biological_processresponse to heat
A0010038biological_processresponse to metal ion
A0016192biological_processvesicle-mediated transport
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0034599biological_processcellular response to oxidative stress
A0042802molecular_functionidentical protein binding
A0043529cellular_componentGET complex
A0044183molecular_functionprotein folding chaperone
A0045048biological_processprotein insertion into ER membrane
A0046685biological_processresponse to arsenic-containing substance
A0046872molecular_functionmetal ion binding
A0051082molecular_functionunfolded protein binding
A0071816biological_processtail-anchored membrane protein insertion into ER membrane
B0000750biological_processpheromone-dependent signal transduction involved in conjugation with cellular fusion
B0005085molecular_functionguanyl-nucleotide exchange factor activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0006457biological_processprotein folding
B0006620biological_processpost-translational protein targeting to endoplasmic reticulum membrane
B0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B0008270molecular_functionzinc ion binding
B0009408biological_processresponse to heat
B0010038biological_processresponse to metal ion
B0016192biological_processvesicle-mediated transport
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0034599biological_processcellular response to oxidative stress
B0042802molecular_functionidentical protein binding
B0043529cellular_componentGET complex
B0044183molecular_functionprotein folding chaperone
B0045048biological_processprotein insertion into ER membrane
B0046685biological_processresponse to arsenic-containing substance
B0046872molecular_functionmetal ion binding
B0051082molecular_functionunfolded protein binding
B0071816biological_processtail-anchored membrane protein insertion into ER membrane
C0000750biological_processpheromone-dependent signal transduction involved in conjugation with cellular fusion
C0005085molecular_functionguanyl-nucleotide exchange factor activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005783cellular_componentendoplasmic reticulum
C0005789cellular_componentendoplasmic reticulum membrane
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0006457biological_processprotein folding
C0006620biological_processpost-translational protein targeting to endoplasmic reticulum membrane
C0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
C0008270molecular_functionzinc ion binding
C0009408biological_processresponse to heat
C0010038biological_processresponse to metal ion
C0016192biological_processvesicle-mediated transport
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0034599biological_processcellular response to oxidative stress
C0042802molecular_functionidentical protein binding
C0043529cellular_componentGET complex
C0044183molecular_functionprotein folding chaperone
C0045048biological_processprotein insertion into ER membrane
C0046685biological_processresponse to arsenic-containing substance
C0046872molecular_functionmetal ion binding
C0051082molecular_functionunfolded protein binding
C0071816biological_processtail-anchored membrane protein insertion into ER membrane
D0000750biological_processpheromone-dependent signal transduction involved in conjugation with cellular fusion
D0005085molecular_functionguanyl-nucleotide exchange factor activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005783cellular_componentendoplasmic reticulum
D0005789cellular_componentendoplasmic reticulum membrane
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0006457biological_processprotein folding
D0006620biological_processpost-translational protein targeting to endoplasmic reticulum membrane
D0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
D0008270molecular_functionzinc ion binding
D0009408biological_processresponse to heat
D0010038biological_processresponse to metal ion
D0016192biological_processvesicle-mediated transport
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0034599biological_processcellular response to oxidative stress
D0042802molecular_functionidentical protein binding
D0043529cellular_componentGET complex
D0044183molecular_functionprotein folding chaperone
D0045048biological_processprotein insertion into ER membrane
D0046685biological_processresponse to arsenic-containing substance
D0046872molecular_functionmetal ion binding
D0051082molecular_functionunfolded protein binding
D0071816biological_processtail-anchored membrane protein insertion into ER membrane
Functional Information from PDB Data
site_idAC1
Number of Residues23
DetailsBINDING SITE FOR RESIDUE ADP A 401
ChainResidue
AGLY28
AGLY319
AILE321
APHE330
AALF402
AMG403
AHOH2066
AHOH2118
AHOH2131
AHOH2132
AHOH2133
AVAL29
AHOH2134
BLYS26
BGLU245
BLEU247
AGLY30
ALYS31
ATHR32
ATHR33
AASN272
APRO315
ACYS317

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE ALF A 402
ChainResidue
AGLY27
AGLY28
ALYS31
AASP57
AASN61
APRO169
AADP401
AMG403
AHOH2023
AHOH2025
AHOH2029
AHOH2066
AHOH2133
BLYS26
BGLY27

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 403
ChainResidue
ATHR32
AADP401
AALF402
AHOH2025
AHOH2066
AHOH2133

site_idAC4
Number of Residues24
DetailsBINDING SITE FOR RESIDUE ADP B 401
ChainResidue
ALYS26
AGLU245
ALEU247
AHOH2102
BGLY28
BVAL29
BGLY30
BLYS31
BTHR32
BTHR33
BASN272
BPRO315
BLEU316
BCYS317
BGLY319
BGLU320
BILE321
BPHE330
BALF402
BMG403
BHOH2078
BHOH2137
BHOH2142
BHOH2154

site_idAC5
Number of Residues15
DetailsBINDING SITE FOR RESIDUE ALF B 402
ChainResidue
ALYS26
AGLY27
AHOH2090
BGLY27
BGLY28
BLYS31
BASP57
BASN61
BPRO169
BADP401
BMG403
BHOH2031
BHOH2032
BHOH2078
BHOH2154

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 403
ChainResidue
BTHR32
BADP401
BALF402
BHOH2031
BHOH2078
BHOH2154

site_idAC7
Number of Residues23
DetailsBINDING SITE FOR RESIDUE ADP C 401
ChainResidue
CGLY319
CILE321
CPHE330
CALF402
CMG403
CHOH2033
CHOH2066
CHOH2104
CHOH2105
CHOH2118
DLYS26
DGLU245
DLEU247
CGLY28
CVAL29
CGLY30
CLYS31
CTHR32
CTHR33
CASN272
CPRO315
CLEU316
CCYS317

site_idAC8
Number of Residues15
DetailsBINDING SITE FOR RESIDUE ALF C 402
ChainResidue
CGLY27
CGLY28
CLYS31
CASP57
CASN61
CPRO169
CADP401
CMG403
CHOH2026
CHOH2027
CHOH2033
CHOH2034
CHOH2066
DLYS26
DGLY27

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG C 403
ChainResidue
CTHR32
CADP401
CALF402
CHOH2026
CHOH2033
CHOH2066

site_idBC1
Number of Residues23
DetailsBINDING SITE FOR RESIDUE ADP D 401
ChainResidue
CLYS26
CGLU245
CLEU247
CHOH2093
DGLY28
DVAL29
DGLY30
DLYS31
DTHR32
DTHR33
DASN272
DPRO315
DCYS317
DGLY319
DGLU320
DILE321
DPHE330
DALF402
DMG403
DHOH2028
DHOH2055
DHOH2094
DHOH2097

site_idBC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE ALF D 402
ChainResidue
CLYS26
CGLY27
DGLY27
DGLY28
DLYS31
DASP57
DASN61
DPRO169
DADP401
DMG403
DHOH2022
DHOH2023
DHOH2028
DHOH2029
DHOH2055

site_idBC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG D 403
ChainResidue
DTHR32
DADP401
DALF402
DHOH2022
DHOH2028
DHOH2055

site_idBC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1353
ChainResidue
ACYS285
ACYS288
BCYS285
BCYS288

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN C 1352
ChainResidue
CCYS285
CCYS288
DCYS285
DCYS288

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE:
ChainResidueDetails
AASP57
BASP57
CASP57
DASP57

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING:
ChainResidueDetails
ALYS26
CGLU245
CASN272
CPRO315
DLYS26
DGLU245
DASN272
DPRO315
AGLU245
AASN272
APRO315
BLYS26
BGLU245
BASN272
BPRO315
CLYS26

site_idSWS_FT_FI3
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03112, ECO:0000269|PubMed:19675567
ChainResidueDetails
ACYS285
ACYS288
BCYS285
BCYS288
CCYS285
CCYS288
DCYS285
DCYS288

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PDB entries from 2024-09-11

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