2WJ8

Respiratory Syncitial Virus RiboNucleoProtein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0019013	cellular_component	viral nucleocapsid
A	0019028	cellular_component	viral capsid
A	0019029	cellular_component	helical viral capsid
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
A	0030430	cellular_component	host cell cytoplasm
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039503	biological_process	obsolete suppression by virus of host innate immune response
A	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
A	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
A	0044423	cellular_component	virion component
A	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0019013	cellular_component	viral nucleocapsid
B	0019028	cellular_component	viral capsid
B	0019029	cellular_component	helical viral capsid
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
B	0030430	cellular_component	host cell cytoplasm
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039503	biological_process	obsolete suppression by virus of host innate immune response
B	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
B	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
B	0044423	cellular_component	virion component
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0019013	cellular_component	viral nucleocapsid
C	0019028	cellular_component	viral capsid
C	0019029	cellular_component	helical viral capsid
C	0019049	biological_process	virus-mediated perturbation of host defense response
C	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
C	0030430	cellular_component	host cell cytoplasm
C	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
C	0039503	biological_process	obsolete suppression by virus of host innate immune response
C	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
C	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
C	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
C	0044423	cellular_component	virion component
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0019013	cellular_component	viral nucleocapsid
D	0019028	cellular_component	viral capsid
D	0019029	cellular_component	helical viral capsid
D	0019049	biological_process	virus-mediated perturbation of host defense response
D	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
D	0030430	cellular_component	host cell cytoplasm
D	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
D	0039503	biological_process	obsolete suppression by virus of host innate immune response
D	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
D	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
D	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
D	0044423	cellular_component	virion component
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0019013	cellular_component	viral nucleocapsid
E	0019028	cellular_component	viral capsid
E	0019029	cellular_component	helical viral capsid
E	0019049	biological_process	virus-mediated perturbation of host defense response
E	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
E	0030430	cellular_component	host cell cytoplasm
E	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
E	0039503	biological_process	obsolete suppression by virus of host innate immune response
E	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
E	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
E	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
E	0044423	cellular_component	virion component
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0019013	cellular_component	viral nucleocapsid
F	0019028	cellular_component	viral capsid
F	0019029	cellular_component	helical viral capsid
F	0019049	biological_process	virus-mediated perturbation of host defense response
F	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
F	0030430	cellular_component	host cell cytoplasm
F	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
F	0039503	biological_process	obsolete suppression by virus of host innate immune response
F	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
F	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
F	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
F	0044423	cellular_component	virion component
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0019013	cellular_component	viral nucleocapsid
G	0019028	cellular_component	viral capsid
G	0019029	cellular_component	helical viral capsid
G	0019049	biological_process	virus-mediated perturbation of host defense response
G	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
G	0030430	cellular_component	host cell cytoplasm
G	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
G	0039503	biological_process	obsolete suppression by virus of host innate immune response
G	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
G	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
G	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
G	0044423	cellular_component	virion component
G	1990904	cellular_component	ribonucleoprotein complex
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0019013	cellular_component	viral nucleocapsid
H	0019028	cellular_component	viral capsid
H	0019029	cellular_component	helical viral capsid
H	0019049	biological_process	virus-mediated perturbation of host defense response
H	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
H	0030430	cellular_component	host cell cytoplasm
H	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
H	0039503	biological_process	obsolete suppression by virus of host innate immune response
H	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
H	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
H	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
H	0044423	cellular_component	virion component
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0019013	cellular_component	viral nucleocapsid
I	0019028	cellular_component	viral capsid
I	0019029	cellular_component	helical viral capsid
I	0019049	biological_process	virus-mediated perturbation of host defense response
I	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
I	0030430	cellular_component	host cell cytoplasm
I	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
I	0039503	biological_process	obsolete suppression by virus of host innate immune response
I	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
I	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
I	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
I	0044423	cellular_component	virion component
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0019013	cellular_component	viral nucleocapsid
J	0019028	cellular_component	viral capsid
J	0019029	cellular_component	helical viral capsid
J	0019049	biological_process	virus-mediated perturbation of host defense response
J	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
J	0030430	cellular_component	host cell cytoplasm
J	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
J	0039503	biological_process	obsolete suppression by virus of host innate immune response
J	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
J	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
J	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
J	0044423	cellular_component	virion component
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0019013	cellular_component	viral nucleocapsid
K	0019028	cellular_component	viral capsid
K	0019029	cellular_component	helical viral capsid
K	0019049	biological_process	virus-mediated perturbation of host defense response
K	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
K	0030430	cellular_component	host cell cytoplasm
K	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
K	0039503	biological_process	obsolete suppression by virus of host innate immune response
K	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
K	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
K	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
K	0044423	cellular_component	virion component
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0019013	cellular_component	viral nucleocapsid
L	0019028	cellular_component	viral capsid
L	0019029	cellular_component	helical viral capsid
L	0019049	biological_process	virus-mediated perturbation of host defense response
L	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
L	0030430	cellular_component	host cell cytoplasm
L	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
L	0039503	biological_process	obsolete suppression by virus of host innate immune response
L	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
L	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
L	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
L	0044423	cellular_component	virion component
L	1990904	cellular_component	ribonucleoprotein complex
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0019013	cellular_component	viral nucleocapsid
M	0019028	cellular_component	viral capsid
M	0019029	cellular_component	helical viral capsid
M	0019049	biological_process	virus-mediated perturbation of host defense response
M	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
M	0030430	cellular_component	host cell cytoplasm
M	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
M	0039503	biological_process	obsolete suppression by virus of host innate immune response
M	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
M	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
M	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
M	0044423	cellular_component	virion component
M	1990904	cellular_component	ribonucleoprotein complex
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0019013	cellular_component	viral nucleocapsid
N	0019028	cellular_component	viral capsid
N	0019029	cellular_component	helical viral capsid
N	0019049	biological_process	virus-mediated perturbation of host defense response
N	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
N	0030430	cellular_component	host cell cytoplasm
N	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
N	0039503	biological_process	obsolete suppression by virus of host innate immune response
N	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
N	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
N	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
N	0044423	cellular_component	virion component
N	1990904	cellular_component	ribonucleoprotein complex
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0019013	cellular_component	viral nucleocapsid
O	0019028	cellular_component	viral capsid
O	0019029	cellular_component	helical viral capsid
O	0019049	biological_process	virus-mediated perturbation of host defense response
O	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
O	0030430	cellular_component	host cell cytoplasm
O	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
O	0039503	biological_process	obsolete suppression by virus of host innate immune response
O	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
O	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
O	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
O	0044423	cellular_component	virion component
O	1990904	cellular_component	ribonucleoprotein complex
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0019013	cellular_component	viral nucleocapsid
P	0019028	cellular_component	viral capsid
P	0019029	cellular_component	helical viral capsid
P	0019049	biological_process	virus-mediated perturbation of host defense response
P	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
P	0030430	cellular_component	host cell cytoplasm
P	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
P	0039503	biological_process	obsolete suppression by virus of host innate immune response
P	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
P	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
P	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
P	0044423	cellular_component	virion component
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0019013	cellular_component	viral nucleocapsid
Q	0019028	cellular_component	viral capsid
Q	0019029	cellular_component	helical viral capsid
Q	0019049	biological_process	virus-mediated perturbation of host defense response
Q	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Q	0030430	cellular_component	host cell cytoplasm
Q	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
Q	0039503	biological_process	obsolete suppression by virus of host innate immune response
Q	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
Q	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
Q	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
Q	0044423	cellular_component	virion component
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0019013	cellular_component	viral nucleocapsid
R	0019028	cellular_component	viral capsid
R	0019029	cellular_component	helical viral capsid
R	0019049	biological_process	virus-mediated perturbation of host defense response
R	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
R	0030430	cellular_component	host cell cytoplasm
R	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
R	0039503	biological_process	obsolete suppression by virus of host innate immune response
R	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
R	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
R	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
R	0044423	cellular_component	virion component
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0019013	cellular_component	viral nucleocapsid
S	0019028	cellular_component	viral capsid
S	0019029	cellular_component	helical viral capsid
S	0019049	biological_process	virus-mediated perturbation of host defense response
S	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
S	0030430	cellular_component	host cell cytoplasm
S	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
S	0039503	biological_process	obsolete suppression by virus of host innate immune response
S	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
S	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
S	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
S	0044423	cellular_component	virion component
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0019013	cellular_component	viral nucleocapsid
T	0019028	cellular_component	viral capsid
T	0019029	cellular_component	helical viral capsid
T	0019049	biological_process	virus-mediated perturbation of host defense response
T	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
T	0030430	cellular_component	host cell cytoplasm
T	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
T	0039503	biological_process	obsolete suppression by virus of host innate immune response
T	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
T	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
T	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
T	0044423	cellular_component	virion component
T	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BO4 A 2001

Chain	Residue
A	ASN93
A	GLY94
A	HOH3029
G	ASN93
G	GLY94
G	THR115

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 B 2001

Chain	Residue
F	GLY94
F	THR115
B	ASN93
B	GLY94
F	ASN93

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 C 2001

Chain	Residue
C	ASN93
C	GLY94
E	ASN93
E	GLY94
E	THR115

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 D 2001

Chain	Residue
D	ASN93
D	ASN93
D	GLY94
D	GLY94
D	THR115

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 H 2001

Chain	Residue
H	ASN93
H	GLY94
J	ASN93
J	GLY94
J	THR115

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 I 2001

Chain	Residue
I	ASN93
I	ASN93
I	GLY94
I	GLY94
I	THR115

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 K 2001

Chain	Residue
K	ASN93
K	GLY94
S	ASN93
S	GLY94
S	THR115

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 L 2001

Chain	Residue
L	ASN93
L	GLY94
R	ASN93
R	GLY94
R	THR115

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 M 2001

Chain	Residue
M	ASN93
M	GLY94
Q	ASN93
Q	GLY94
Q	THR115

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 N 2001

Chain	Residue
N	ASN93
N	GLY94
P	ASN93
P	GLY94
P	THR115

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BO4 O 2001

Chain	Residue
O	ASN93
O	ASN93
O	GLY94
O	GLY94

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BO4 T 2001

Chain	Residue
T	ASN93
T	ASN93
T	GLY94
T	GLY94
T	THR115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:22019509

Chain	Residue	Details
A	TYR38
J	TYR38
K	TYR38
L	TYR38
M	TYR38
N	TYR38
O	TYR38
P	TYR38
Q	TYR38
R	TYR38
S	TYR38
B	TYR38
T	TYR38
C	TYR38
D	TYR38
E	TYR38
F	TYR38
G	TYR38
H	TYR38
I	TYR38

---