Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0006508 | biological_process | proteolysis |
| X | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS X 1828 |
| Chain | Residue |
| X | ASP589 |
| X | SER641 |
| X | TYR663 |
| X | ASN664 |
| X | TYR665 |
| X | TYR703 |
| X | HOH2245 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA X 1829 |
| Chain | Residue |
| X | ASP757 |
| X | GLY777 |
| X | HOH2165 |
| X | HOH2167 |
| X | GLU739 |
| X | ASN740 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL X 1830 |
| Chain | Residue |
| X | SER640 |
| X | LYS667 |
| X | TYR735 |
| X | HOH2037 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL X 1831 |
| Chain | Residue |
| X | ASP634 |
| X | ARG635 |
| X | CYS636 |
| X | ASP637 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS X 1832 |
| Chain | Residue |
| X | GLU588 |
| X | ASP589 |
| X | TYR663 |
| X | HOH2246 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL X 1833 |
| Chain | Residue |
| X | LYS701 |
| X | TRP789 |
| X | GLY790 |
| X | PRO791 |
| X | TYR792 |
| X | TRP793 |
| X | HOH2028 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS X 1834 |
| Chain | Residue |
| X | CYS809 |
| X | HIS810 |
| X | ASN812 |
| X | HOH2247 |
| X | HOH2248 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL X 1835 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA X 1836 |
| Chain | Residue |
| X | GLU709 |
| X | ASP758 |
| X | HOH2087 |
| X | HOH2129 |
| X | HOH2234 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS X 1837 |
| Chain | Residue |
| X | ASN626 |
| X | TYR628 |
| X | TYR652 |
| X | CYS672 |
| X | HOH2076 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS X 1838 |
| Chain | Residue |
| X | ARG710 |
| X | ASN714 |
| X | HOH2133 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS X 1839 |
| Chain | Residue |
| X | SER747 |
| X | GLY748 |
| X | LYS749 |
| X | GLY794 |
| X | ASP795 |
| X | HOH2207 |
Functional Information from PROSITE/UniProt
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. ADHAVNIVGYG |
| Chain | Residue | Details |
| X | ALA760-GLY770 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvRNSWgpyWGdeGYFkV |
| Chain | Residue | Details |
| X | TYR782-VAL801 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Ancestral active site","evidences":[{"source":"PubMed","id":"19591843","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25599609","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 9pap |
| Chain | Residue | Details |
| X | HIS762 | |
| X | GLN590 | |
| X | ASN787 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 9pap |
| Chain | Residue | Details |
| X | HIS762 | |
| X | GLN590 | |
| X | ASN787 | |
| X | SER596 | |
