2W8F

Aplysia californica AChBP bound to in silico compound 31

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0007165	biological_process	signal transduction
A	0007268	biological_process	chemical synaptic transmission
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042391	biological_process	regulation of membrane potential
A	0042802	molecular_function	identical protein binding
A	0043005	cellular_component	neuron projection
A	0045202	cellular_component	synapse
A	0046872	molecular_function	metal ion binding
A	0050877	biological_process	nervous system process
A	0060078	biological_process	regulation of postsynaptic membrane potential
A	0060079	biological_process	excitatory postsynaptic potential
A	0098794	cellular_component	postsynapse
A	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0007165	biological_process	signal transduction
B	0007268	biological_process	chemical synaptic transmission
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042391	biological_process	regulation of membrane potential
B	0042802	molecular_function	identical protein binding
B	0043005	cellular_component	neuron projection
B	0045202	cellular_component	synapse
B	0046872	molecular_function	metal ion binding
B	0050877	biological_process	nervous system process
B	0060078	biological_process	regulation of postsynaptic membrane potential
B	0060079	biological_process	excitatory postsynaptic potential
B	0098794	cellular_component	postsynapse
B	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0007165	biological_process	signal transduction
C	0007268	biological_process	chemical synaptic transmission
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042391	biological_process	regulation of membrane potential
C	0042802	molecular_function	identical protein binding
C	0043005	cellular_component	neuron projection
C	0045202	cellular_component	synapse
C	0046872	molecular_function	metal ion binding
C	0050877	biological_process	nervous system process
C	0060078	biological_process	regulation of postsynaptic membrane potential
C	0060079	biological_process	excitatory postsynaptic potential
C	0098794	cellular_component	postsynapse
C	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0006811	biological_process	monoatomic ion transport
D	0007165	biological_process	signal transduction
D	0007268	biological_process	chemical synaptic transmission
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042391	biological_process	regulation of membrane potential
D	0042802	molecular_function	identical protein binding
D	0043005	cellular_component	neuron projection
D	0045202	cellular_component	synapse
D	0046872	molecular_function	metal ion binding
D	0050877	biological_process	nervous system process
D	0060078	biological_process	regulation of postsynaptic membrane potential
D	0060079	biological_process	excitatory postsynaptic potential
D	0098794	cellular_component	postsynapse
D	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
E	0005515	molecular_function	protein binding
E	0006811	biological_process	monoatomic ion transport
E	0007165	biological_process	signal transduction
E	0007268	biological_process	chemical synaptic transmission
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042391	biological_process	regulation of membrane potential
E	0042802	molecular_function	identical protein binding
E	0043005	cellular_component	neuron projection
E	0045202	cellular_component	synapse
E	0046872	molecular_function	metal ion binding
E	0050877	biological_process	nervous system process
E	0060078	biological_process	regulation of postsynaptic membrane potential
E	0060079	biological_process	excitatory postsynaptic potential
E	0098794	cellular_component	postsynapse
E	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
F	0005515	molecular_function	protein binding
F	0006811	biological_process	monoatomic ion transport
F	0007165	biological_process	signal transduction
F	0007268	biological_process	chemical synaptic transmission
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
F	0042391	biological_process	regulation of membrane potential
F	0042802	molecular_function	identical protein binding
F	0043005	cellular_component	neuron projection
F	0045202	cellular_component	synapse
F	0046872	molecular_function	metal ion binding
F	0050877	biological_process	nervous system process
F	0060078	biological_process	regulation of postsynaptic membrane potential
F	0060079	biological_process	excitatory postsynaptic potential
F	0098794	cellular_component	postsynapse
F	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
G	0005515	molecular_function	protein binding
G	0006811	biological_process	monoatomic ion transport
G	0007165	biological_process	signal transduction
G	0007268	biological_process	chemical synaptic transmission
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042391	biological_process	regulation of membrane potential
G	0042802	molecular_function	identical protein binding
G	0043005	cellular_component	neuron projection
G	0045202	cellular_component	synapse
G	0046872	molecular_function	metal ion binding
G	0050877	biological_process	nervous system process
G	0060078	biological_process	regulation of postsynaptic membrane potential
G	0060079	biological_process	excitatory postsynaptic potential
G	0098794	cellular_component	postsynapse
G	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
H	0005515	molecular_function	protein binding
H	0006811	biological_process	monoatomic ion transport
H	0007165	biological_process	signal transduction
H	0007268	biological_process	chemical synaptic transmission
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
H	0042391	biological_process	regulation of membrane potential
H	0042802	molecular_function	identical protein binding
H	0043005	cellular_component	neuron projection
H	0045202	cellular_component	synapse
H	0046872	molecular_function	metal ion binding
H	0050877	biological_process	nervous system process
H	0060078	biological_process	regulation of postsynaptic membrane potential
H	0060079	biological_process	excitatory postsynaptic potential
H	0098794	cellular_component	postsynapse
H	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
I	0005515	molecular_function	protein binding
I	0006811	biological_process	monoatomic ion transport
I	0007165	biological_process	signal transduction
I	0007268	biological_process	chemical synaptic transmission
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
I	0042391	biological_process	regulation of membrane potential
I	0042802	molecular_function	identical protein binding
I	0043005	cellular_component	neuron projection
I	0045202	cellular_component	synapse
I	0046872	molecular_function	metal ion binding
I	0050877	biological_process	nervous system process
I	0060078	biological_process	regulation of postsynaptic membrane potential
I	0060079	biological_process	excitatory postsynaptic potential
I	0098794	cellular_component	postsynapse
I	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
J	0005515	molecular_function	protein binding
J	0006811	biological_process	monoatomic ion transport
J	0007165	biological_process	signal transduction
J	0007268	biological_process	chemical synaptic transmission
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
J	0042391	biological_process	regulation of membrane potential
J	0042802	molecular_function	identical protein binding
J	0043005	cellular_component	neuron projection
J	0045202	cellular_component	synapse
J	0046872	molecular_function	metal ion binding
J	0050877	biological_process	nervous system process
J	0060078	biological_process	regulation of postsynaptic membrane potential
J	0060079	biological_process	excitatory postsynaptic potential
J	0098794	cellular_component	postsynapse
J	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BS1 A 1206

Chain	Residue
A	TRP145
A	TYR186
A	CYS189
A	TYR193
B	THR34
B	GLN55
B	ILE116

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE BS1 F 1206

Chain	Residue
F	CYS188
F	CYS189
F	GLU191
F	TYR193
G	THR34
G	GLN55
G	ILE116
G	ASP162
F	TRP145
F	TYR186

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