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2W57

Crystal structure of the Vibrio cholerae ferric uptake regulator (Fur) reveals structural rearrangement of the DNA-binding domains

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006351biological_processDNA-templated transcription
A0006355biological_processregulation of DNA-templated transcription
A0008270molecular_functionzinc ion binding
A0045892biological_processnegative regulation of DNA-templated transcription
A0046872molecular_functionmetal ion binding
A1900705biological_processnegative regulation of siderophore biosynthetic process
B0000976molecular_functiontranscription cis-regulatory region binding
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006351biological_processDNA-templated transcription
B0006355biological_processregulation of DNA-templated transcription
B0008270molecular_functionzinc ion binding
B0045892biological_processnegative regulation of DNA-templated transcription
B0046872molecular_functionmetal ion binding
B1900705biological_processnegative regulation of siderophore biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 201
ChainResidue
AHIS87
AASP89
AGLU108
AHIS125

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 202
ChainResidue
AHIS33
AGLU81
AHIS88
AHIS90

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 201
ChainResidue
BASP89
BGLU108
BHIS125
BHIS87

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 202
ChainResidue
BHIS33
BGLU81
BHIS88
BHIS90

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

250359

PDB entries from 2026-03-11

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