Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DRO A1166 |
| Chain | Residue |
| A | PHE63 |
| A | TYR67 |
| A | ASP70 |
| A | MET74 |
| A | VAL92 |
| A | GLU95 |
| A | LEU96 |
| A | ALA108 |
| A | PHE112 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DRO B1164 |
| Chain | Residue |
| B | PHE63 |
| B | TYR67 |
| B | ASP70 |
| B | PHE71 |
| B | MET74 |
| B | GLU95 |
| B | LEU96 |
| B | ALA108 |
| B | PHE112 |
| B | HOH2102 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFeFGG |
| Chain | Residue | Details |
| A | LEU96-GLY114 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqdnGGWDaFV |
| Chain | Residue | Details |
| A | TRP147-VAL158 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VhktLReAGDDFSRR |
| Chain | Residue | Details |
| A | VAL52-ARG66 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. DNREIVmKYIHYKLSQRGYeW |
| Chain | Residue | Details |
| A | ASP10-TRP30 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Region: {"description":"Required for interaction with SEPTIN4 isoform ARTS. Required XIAP-mediated ubiquitination and apoptosis","evidences":[{"source":"PubMed","id":"29020630","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Motif: {"description":"BH4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00025","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 28 |
| Details | Motif: {"description":"BH3","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 38 |
| Details | Motif: {"description":"BH1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 30 |
| Details | Motif: {"description":"BH2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
