Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | ARG116 |
| A | HIS118 |
| A | HIS141 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 402 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 403 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 501 |
| Chain | Residue |
| A | HOH2157 |
| A | HOH2322 |
| A | GLU24 |
| A | SER56 |
| A | TRP216 |
| A | ARG237 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 502 |
| Chain | Residue |
| A | ARG125 |
| A | GLY126 |
| A | SER127 |
| A | ALA135 |
| A | PHE274 |
| A | HOH2323 |
| A | HOH2324 |
| A | HOH2325 |
| A | HOH2326 |
| A | HOH2327 |
| A | HOH2328 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | VAL98 |
| A | GLU109 |
| A | GLU111 |
| A | PRO279 |
| A | HOH2164 |
| A | HOH2329 |
| A | HOH2330 |
| A | HOH2331 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 504 |
| Chain | Residue |
| A | GLY173 |
| A | LYS174 |
| A | HOH2332 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | LEU149 |
| A | HOH2158 |
| A | HOH2159 |
| A | HOH2169 |
| A | HOH2333 |
| A | HOH2334 |
| A | HOH2335 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | SER56 |
| A | ALA59 |
| A | ALA287 |
| A | PHE289 |
| A | GLN290 |
| A | HOH2049 |
| A | HOH2336 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 601 |
| Chain | Residue |
| A | ASP154 |
| A | UNX602 |
| A | UNX603 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX A 602 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE UNX A 603 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVnfkaFpmELHLI |
| Chain | Residue | Details |
| A | SER127-ILE143 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 262 |
| Details | Domain: {"description":"Alpha-carbonic anhydrase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01134","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"P00918","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Ancestral zinc ligand"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ca2 |
| Chain | Residue | Details |
| A | THR223 | |
| A | HIS87 | |
