2W0F

Potassium Channel KcsA-Fab Complex with Tetraoctylammonium

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO C 1125

Chain	Residue
C	HIS124
C	HIS124
C	HIS124
C	HIS124

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE F09 C 1126

Chain	Residue
A	ARG57
C	HOH2037

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DGA C 1127

Chain	Residue
C	PRO63
C	LEU66
C	LEU86
C	ARG89
C	HOH2007
C	HOH2039
C	HOH2040
C	HOH2041
C	LEU41
C	TYR45
C	TYR62

---

site_id	AC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HX0 C 1128

Chain	Residue
C	ALA73
C	ALA73
C	ALA73
C	ALA73
C	THR74
C	THR74
C	THR74
C	THR74
C	THR75
C	THR75
C	THR75
C	THR75
C	GLY99
C	GLY99
C	GLY99
C	GLY99
C	PHE103
C	PHE103
C	PHE103
C	PHE103
C	HOH2018
C	HOH2018
C	HOH2018
C	HOH2018

---

site_id	AC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 1129

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K1131
C	K1131
C	K1131
C	K1131
C	K1132
C	K1132
C	K1132
C	K1132

---

site_id	AC6
Number of Residues	16
Details	BINDING SITE FOR RESIDUE K C 1130

Chain	Residue
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K1134
C	K1134
C	K1134
C	K1134
C	K1135
C	K1135
C	K1135
C	K1135

---

site_id	AC7
Number of Residues	24
Details	BINDING SITE FOR RESIDUE K C 1131

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	K1129
C	K1129
C	K1129
C	K1129
C	K1133
C	K1133
C	K1133
C	K1133
C	K1135
C	K1135
C	K1135
C	K1135
C	HOH2020
C	HOH2020
C	HOH2020
C	HOH2020

---

site_id	AC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE K C 1132

Chain	Residue
C	VAL76
C	VAL76
C	K1129
C	K1129
C	K1129
C	K1129
C	K1133
C	K1133
C	K1133
C	K1133
C	HOH2020
C	HOH2020
C	HOH2020
C	HOH2020
C	THR75
C	THR75
C	THR75
C	THR75
C	VAL76
C	VAL76

---

site_id	AC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 1133

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K1131
C	K1131
C	K1131
C	K1131
C	K1132
C	K1132
C	K1132
C	K1132

---

site_id	BC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE K C 1134

Chain	Residue
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K1130
C	K1130
C	K1130
C	K1130
C	K1135
C	K1135
C	K1135
C	K1135

---

site_id	BC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE K C 1135

Chain	Residue
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	K1130
C	K1130
C	K1130
C	K1130
C	K1131
C	K1131
C	K1131
C	K1131
C	K1134
C	K1134
C	K1134
C	K1134
C	HOH2020
C	HOH2020
C	HOH2020
C	HOH2020

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	7
Details	Intramembrane: {"description":"Pore-forming"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

---