Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 7X6 A 1889 |
| Chain | Residue |
| A | ILE621 |
| A | GLU697 |
| A | GLY699 |
| A | LEU747 |
| A | HOH2026 |
| A | HOH2249 |
| A | HOH2250 |
| A | HOH2251 |
| A | HOH2253 |
| A | ALA645 |
| A | LYS647 |
| A | GLU664 |
| A | ILE677 |
| A | ILE691 |
| A | THR693 |
| A | GLU694 |
| A | MET696 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 1890 |
| Chain | Residue |
| A | ASP740 |
| A | ASP758 |
| A | MG1891 |
| A | HOH2113 |
| A | HOH2124 |
| A | HOH2125 |
| A | HOH2126 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1891 |
| Chain | Residue |
| A | ASP740 |
| A | ASP758 |
| A | MG1890 |
| A | HOH2112 |
| A | HOH2125 |
| A | HOH2128 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1892 |
| Chain | Residue |
| A | HOH2087 |
| A | HOH2088 |
| A | HOH2164 |
| A | HOH2165 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGAGEFGEVCrGrlkapgkkesc.......VAIK |
| Chain | Residue | Details |
| A | ILE621-LYS647 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLAARNILV |
| Chain | Residue | Details |
| A | TYR736-VAL748 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ARG744 | |
| A | ASP740 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP740 | |
| A | ALA742 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP740 | |
| A | ASN745 | |
| A | ALA742 | |
