2VWE

Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008083	molecular_function	growth factor activity
A	0008201	molecular_function	heparin binding
A	0016020	cellular_component	membrane
B	0008083	molecular_function	growth factor activity
B	0008201	molecular_function	heparin binding
B	0016020	cellular_component	membrane
C	0002250	biological_process	adaptive immune response
C	0002376	biological_process	immune system process
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
C	0006955	biological_process	immune response
C	0019814	cellular_component	immunoglobulin complex
C	0030183	biological_process	B cell differentiation
C	0042105	cellular_component	alpha-beta T cell receptor complex
C	0071735	cellular_component	IgG immunoglobulin complex
J	0002250	biological_process	adaptive immune response
J	0002376	biological_process	immune system process
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005886	cellular_component	plasma membrane
J	0006955	biological_process	immune response
J	0019814	cellular_component	immunoglobulin complex
J	0030183	biological_process	B cell differentiation
J	0042105	cellular_component	alpha-beta T cell receptor complex
J	0071735	cellular_component	IgG immunoglobulin complex

Functional Information from PROSITE/UniProt

site_id	PS00249
Number of Residues	13
Details	PDGF_1 Platelet-derived growth factor (PDGF) family signature. PSCVtvqRCGGCC

Chain	Residue	Details
A	PRO49-CYS61

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
C	TYR191-HIS197

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