2VVR
Crystal structure of the H99N mutant of ribose-5-phosphate isomerase B from E. coli soaked with ribose 5-phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| A | 0019316 | biological_process | D-allose catabolic process |
| B | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| B | 0019316 | biological_process | D-allose catabolic process |
| C | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| C | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| C | 0019316 | biological_process | D-allose catabolic process |
| D | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| D | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| D | 0019316 | biological_process | D-allose catabolic process |
| E | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0006098 | biological_process | pentose-phosphate shunt |
| E | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| E | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| E | 0019316 | biological_process | D-allose catabolic process |
| F | 0004751 | molecular_function | ribose-5-phosphate isomerase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0006098 | biological_process | pentose-phosphate shunt |
| F | 0008786 | molecular_function | D-allose 6-phosphate isomerase activity |
| F | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| F | 0019316 | biological_process | D-allose catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18640127","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"18640127","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 54 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P9WKD7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| A | HIS10 | |
| A | ARG137 | |
| A | CYS66 | |
| A | ASP9 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| B | HIS10 | |
| B | ARG137 | |
| B | CYS66 | |
| B | ASP9 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| C | HIS10 | |
| C | ARG137 | |
| C | CYS66 | |
| C | ASP9 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| D | HIS10 | |
| D | ARG137 | |
| D | CYS66 | |
| D | ASP9 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| E | HIS10 | |
| E | ARG137 | |
| E | CYS66 | |
| E | ASP9 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nn4 |
| Chain | Residue | Details |
| F | HIS10 | |
| F | ARG137 | |
| F | CYS66 | |
| F | ASP9 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| A | ASP9 | proton acceptor, proton donor |
| A | CYS66 | proton acceptor, proton donor |
| A | THR68 | proton acceptor, proton donor, proton relay |
| A | ASN99 | proton donor |
| A | HIS134 | proton acceptor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| B | ASP9 | proton acceptor, proton donor |
| B | CYS66 | proton acceptor, proton donor |
| B | THR68 | proton acceptor, proton donor, proton relay |
| B | ASN99 | proton donor |
| B | HIS134 | proton acceptor |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| C | ASP9 | proton acceptor, proton donor |
| C | CYS66 | proton acceptor, proton donor |
| C | THR68 | proton acceptor, proton donor, proton relay |
| C | ASN99 | proton donor |
| C | HIS134 | proton acceptor |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| D | ASP9 | proton acceptor, proton donor |
| D | CYS66 | proton acceptor, proton donor |
| D | THR68 | proton acceptor, proton donor, proton relay |
| D | ASN99 | proton donor |
| D | HIS134 | proton acceptor |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| E | ASP9 | proton acceptor, proton donor |
| E | CYS66 | proton acceptor, proton donor |
| E | THR68 | proton acceptor, proton donor, proton relay |
| E | ASN99 | proton donor |
| E | HIS134 | proton acceptor |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 680 |
| Chain | Residue | Details |
| F | ASP9 | proton acceptor, proton donor |
| F | CYS66 | proton acceptor, proton donor |
| F | THR68 | proton acceptor, proton donor, proton relay |
| F | ASN99 | proton donor |
| F | HIS134 | proton acceptor |
