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2VV4

hPPARgamma Ligand binding domain in complex with 6-oxoOTE

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE 6OC A 1476
ChainResidue
ACYS285
AHIS449
ATYR473
AARG288
ASER289
AHIS323
ATYR327
ALEU340
AILE341
ASER342
AMET364

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE 6OB B 1475
ChainResidue
BILE281
BCYS285
BARG288
BSER289
BILE326
BLEU333
BILE341

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
BTHR316
BLEU353

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
BSER254

226707

PDB entries from 2024-10-30

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