2VTF
X-ray crystal structure of the Endo-beta-N-acetylglucosaminidase from Arthrobacter protophormiae E173Q mutant reveals a TIM barrel catalytic domain and two ancillary domains
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0033925 | molecular_function | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0033925 | molecular_function | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE B3P A 1618 |
| Chain | Residue |
| A | GLU37 |
| A | HOH2757 |
| A | HOH2758 |
| A | HOH2759 |
| A | HOH2760 |
| A | HOH2761 |
| A | ARG115 |
| A | THR350 |
| A | SER353 |
| A | HOH2477 |
| A | HOH2740 |
| A | HOH2754 |
| A | HOH2755 |
| A | HOH2756 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE B3P A 1619 |
| Chain | Residue |
| A | LEU135 |
| A | GLU139 |
| A | ASP178 |
| A | GLY180 |
| A | THR181 |
| A | HOH2233 |
| A | HOH2234 |
| A | HOH2237 |
| A | HOH2282 |
| A | HOH2283 |
| A | HOH2763 |
| A | HOH2764 |
| A | HOH2765 |
| A | HOH2766 |
| B | PHE12 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE B3P B 1620 |
| Chain | Residue |
| B | GLU139 |
| B | GLY180 |
| B | THR181 |
| B | HOH2199 |
| B | HOH2203 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE B3P B 1621 |
| Chain | Residue |
| B | GLU37 |
| B | ARG115 |
| B | THR350 |
| B | SER353 |
| B | HOH2421 |
| B | HOH2703 |
| B | HOH2727 |
| B | HOH2728 |
| B | HOH2729 |
| B | HOH2730 |
| B | HOH2731 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE B 1622 |
| Chain | Residue |
| B | HIS54 |
| B | GLY199 |
| B | HIS201 |
| B | TYR266 |
| B | HOH2153 |
| B | HOH2732 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE B 1623 |
| Chain | Residue |
| B | LYS373 |
| B | TYR563 |
| B | LYS568 |
| B | HIS596 |
| B | GLU598 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 1620 |
| Chain | Residue |
| A | HIS54 |
| A | GLY199 |
| A | HIS201 |
| A | TYR266 |
| A | HOH2767 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PGE A 1621 |
| Chain | Residue |
| A | TYR563 |
| A | LYS570 |
| A | GLU600 |
