2VRT

Crystal Structure of E. coli RNase E possessing M1 RNA fragments - Catalytic Domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0004540	molecular_function	RNA nuclease activity
A	0006396	biological_process	RNA processing
A	0008995	molecular_function	ribonuclease E activity
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0004540	molecular_function	RNA nuclease activity
B	0006396	biological_process	RNA processing
B	0008995	molecular_function	ribonuclease E activity
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0004540	molecular_function	RNA nuclease activity
C	0006396	biological_process	RNA processing
C	0008995	molecular_function	ribonuclease E activity
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding
D	0004540	molecular_function	RNA nuclease activity
D	0006396	biological_process	RNA processing
D	0008995	molecular_function	ribonuclease E activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A1506

Chain	Residue
A	CYS404
A	CYS407
B	CYS404
B	CYS407

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D1509

Chain	Residue
C	CYS404
C	CYS407
D	CYS404
D	CYS407

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Region: {"description":"Interaction with RNA 5'-terminal monophosphate"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16237448","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15779893","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18682225","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	Region: {"description":"Required for zinc-mediated homotetramerization and catalytic activity"}

Chain

Residue

Details

---