2VNK

X-RAY STRUCTURE OF THE FERREDOXIN-NADP(H) REDUCTASE FROM RHODOBACTER CAPSULATUS IN COMPLEX WITH NADP. FORM III AT 1.93 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004324	molecular_function	ferredoxin-NADP+ reductase activity
A	0005737	cellular_component	cytoplasm
A	0016491	molecular_function	oxidoreductase activity
A	0034599	biological_process	cellular response to oxidative stress
A	0042167	biological_process	heme catabolic process
B	0000166	molecular_function	nucleotide binding
B	0004324	molecular_function	ferredoxin-NADP+ reductase activity
B	0005737	cellular_component	cytoplasm
B	0016491	molecular_function	oxidoreductase activity
B	0034599	biological_process	cellular response to oxidative stress
B	0042167	biological_process	heme catabolic process
C	0000166	molecular_function	nucleotide binding
C	0004324	molecular_function	ferredoxin-NADP+ reductase activity
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0034599	biological_process	cellular response to oxidative stress
C	0042167	biological_process	heme catabolic process
D	0000166	molecular_function	nucleotide binding
D	0004324	molecular_function	ferredoxin-NADP+ reductase activity
D	0005737	cellular_component	cytoplasm
D	0016491	molecular_function	oxidoreductase activity
D	0034599	biological_process	cellular response to oxidative stress
D	0042167	biological_process	heme catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	30
Details	BINDING SITE FOR RESIDUE FAD A 273

Chain	Residue
A	ARG64
A	PRO88
A	LEU89
A	THR90
A	THR130
A	ALA133
A	LYS265
A	ALA266
A	PHE267
A	VAL268
A	GLU270
A	ALA65
A	GLY271
A	ILE272
A	HOH2057
A	HOH2058
A	HOH2205
A	HOH2209
A	HOH2210
A	HOH2211
A	HOH2212
A	HOH2213
A	TYR66
A	HOH2214
A	SER67
A	TYR80
A	SER81
A	ILE82
A	VAL84
A	GLY87

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAP A 274

Chain	Residue
A	THR128
A	CYS157
A	ARG158
A	THR194
A	ARG195
A	ARG203
A	THR205
A	ALA236
A	PHE237
A	ASP240
A	GLU270
A	HOH2166
A	HOH2215
A	HOH2216
A	HOH2217
A	HOH2218
A	HOH2219

---

site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FAD B 273

Chain	Residue
B	ARG64
B	ALA65
B	TYR66
B	SER67
B	TYR80
B	SER81
B	ILE82
B	VAL84
B	GLY87
B	PRO88
B	LEU89
B	THR90
B	THR130
B	ALA133
B	LYS265
B	ALA266
B	PHE267
B	VAL268
B	GLY269
B	HOH2038
B	HOH2039
B	HOH2203
B	HOH2206
B	HOH2207
B	HOH2208
B	HOH2209
B	HOH2210
B	HOH2211

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE NAP B 274

Chain	Residue
B	THR128
B	CYS157
B	ARG158
B	THR194
B	ARG195
B	ARG203
B	THR205
B	ALA236
B	PHE237
B	ASP240
B	HOH2104
B	HOH2212
B	HOH2213
B	HOH2214
B	HOH2215

---

site_id	AC5
Number of Residues	31
Details	BINDING SITE FOR RESIDUE FAD C 273

Chain	Residue
C	PRO88
C	LEU89
C	THR90
C	THR130
C	ALA133
C	LYS265
C	ALA266
C	PHE267
C	VAL268
C	GLY269
C	GLU270
C	GLY271
C	ILE272
C	HOH2060
C	HOH2061
C	HOH2226
C	HOH2227
C	HOH2228
C	HOH2229
C	HOH2230
C	HOH2231
C	HOH2232
C	ARG64
C	ALA65
C	TYR66
C	SER67
C	TYR80
C	SER81
C	ILE82
C	VAL84
C	GLY87

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAP C 274

Chain	Residue
C	THR128
C	CYS157
C	ARG158
C	THR194
C	ARG195
C	ARG203
C	THR205
C	ALA236
C	PHE237
C	ASP240
C	ILE272
C	HOH2139
C	HOH2175
C	HOH2233
C	HOH2234
C	HOH2235
C	HOH2236

---

site_id	AC7
Number of Residues	28
Details	BINDING SITE FOR RESIDUE FAD D 273

Chain	Residue
D	ARG64
D	ALA65
D	TYR66
D	SER67
D	TYR80
D	SER81
D	ILE82
D	VAL84
D	GLY87
D	PRO88
D	LEU89
D	THR90
D	THR130
D	ALA133
D	LYS265
D	ALA266
D	PHE267
D	VAL268
D	GLY269
D	HOH2038
D	HOH2040
D	HOH2199
D	HOH2202
D	HOH2203
D	HOH2204
D	HOH2205
D	HOH2206
D	HOH2207

---

site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAP D 274

Chain	Residue
D	THR128
D	CYS157
D	ARG158
D	THR194
D	ARG195
D	ARG203
D	THR205
D	ALA236
D	PHE237
D	ASP240
D	HOH2101
D	HOH2208
D	HOH2209
D	HOH2210

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16128574","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18973834","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24016470","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18973834","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16128574","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18973834","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndh

Chain	Residue	Details
A	TYR66

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndh

Chain	Residue	Details
B	TYR66

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndh

Chain	Residue	Details
C	TYR66

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ndh

Chain	Residue	Details
D	TYR66

---