Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE BSD A1386 |
| Chain | Residue |
| A | GLN12 |
| A | GLN73 |
| A | PHE108 |
| A | TRP115 |
| A | ILE126 |
| A | ASP228 |
| A | SER229 |
| A | GLY230 |
| A | THR231 |
| A | THR232 |
| A | ASN233 |
| A | GLY13 |
| A | ARG235 |
| A | SER325 |
| A | ALA335 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | SER35 |
| A | PRO70 |
| A | TYR71 |
| A | THR72 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE BSD B1386 |
| Chain | Residue |
| B | GLN12 |
| B | GLY13 |
| B | LEU30 |
| B | ASP32 |
| B | GLY34 |
| B | SER35 |
| B | VAL69 |
| B | TYR71 |
| B | THR72 |
| B | GLN73 |
| B | PHE108 |
| B | TRP115 |
| B | ASP228 |
| B | SER229 |
| B | GLY230 |
| B | THR231 |
| B | THR232 |
| B | ASN233 |
| B | ARG235 |
| B | SER325 |
| B | ALA335 |
| B | HOH2008 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE BSD C1386 |
| Chain | Residue |
| C | GLY11 |
| C | GLN12 |
| C | GLY13 |
| C | ASP32 |
| C | GLY34 |
| C | SER35 |
| C | VAL69 |
| C | PRO70 |
| C | TYR71 |
| C | THR72 |
| C | GLN73 |
| C | PHE108 |
| C | ILE110 |
| C | TRP115 |
| C | ILE118 |
| C | ASP228 |
| C | SER229 |
| C | GLY230 |
| C | THR231 |
| C | THR232 |
| C | ASN233 |
| C | ARG235 |
| C | ARG307 |
| C | SER325 |
| C | ALA335 |
| C | HOH2225 |
| site_id | AC4 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE BSD D1386 |
| Chain | Residue |
| D | GLY11 |
| D | GLN12 |
| D | GLY13 |
| D | LEU30 |
| D | ASP32 |
| D | GLY34 |
| D | SER35 |
| D | VAL69 |
| D | PRO70 |
| D | TYR71 |
| D | THR72 |
| D | GLN73 |
| D | PHE108 |
| D | ILE110 |
| D | TRP115 |
| D | ASP228 |
| D | SER229 |
| D | GLY230 |
| D | THR231 |
| D | THR232 |
| D | ASN233 |
| D | ARG235 |
| D | ARG307 |
| D | SER325 |
| D | ALA335 |
| D | HOH2117 |
| D | HOH2159 |
| D | HOH2180 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE29-VAL40 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP32 | |
| A | ASP228 | |
| B | ASP32 | |
| B | ASP228 | |
| C | ASP32 | |
| C | ASP228 | |
| D | ASP32 | |
| D | ASP228 | |
| Chain | Residue | Details |
| A | LYS65 | |
| B | LYS218 | |
| B | LYS224 | |
| B | LYS238 | |
| B | LYS239 | |
| B | LYS246 | |
| C | LYS65 | |
| C | LYS214 | |
| C | LYS218 | |
| C | LYS224 | |
| C | LYS238 | |
| A | LYS214 | |
| C | LYS239 | |
| C | LYS246 | |
| D | LYS65 | |
| D | LYS214 | |
| D | LYS218 | |
| D | LYS224 | |
| D | LYS238 | |
| D | LYS239 | |
| D | LYS246 | |
| A | LYS218 | |
| A | LYS224 | |
| A | LYS238 | |
| A | LYS239 | |
| A | LYS246 | |
| B | LYS65 | |
| B | LYS214 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN92 | |
| C | ASN111 | |
| C | ASN162 | |
| C | ASN293 | |
| D | ASN92 | |
| D | ASN111 | |
| D | ASN162 | |
| D | ASN293 | |
| A | ASN111 | |
| A | ASN162 | |
| A | ASN293 | |
| B | ASN92 | |
| B | ASN111 | |
| B | ASN162 | |
| B | ASN293 | |
| C | ASN92 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR231 | |
| A | ASP228 | |
| A | SER35 | |
| A | ASP32 | |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP228 | |
| B | SER35 | |
| B | ASP32 | |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP228 | |
| C | SER35 | |
| C | ASP32 | |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP228 | |
| D | SER35 | |
| D | ASP32 | |
| site_id | CSA13 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP228 | |
| A | SER35 | |
| A | TYR71 | |
| A | ASP32 | |
| site_id | CSA14 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP228 | |
| B | SER35 | |
| B | TYR71 | |
| B | ASP32 | |
| site_id | CSA15 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP228 | |
| C | SER35 | |
| C | TYR71 | |
| C | ASP32 | |
| site_id | CSA16 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP228 | |
| D | SER35 | |
| D | TYR71 | |
| D | ASP32 | |
| site_id | CSA17 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR231 | |
| A | ASP228 | |
| A | ASP32 | |
| A | THR33 | |
| site_id | CSA18 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR231 | |
| B | ASP228 | |
| B | ASP32 | |
| B | THR33 | |
| site_id | CSA19 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | THR231 | |
| C | ASP228 | |
| C | ASP32 | |
| C | THR33 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR231 | |
| B | ASP228 | |
| B | SER35 | |
| B | ASP32 | |
| site_id | CSA20 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | THR231 | |
| D | ASP228 | |
| D | ASP32 | |
| D | THR33 | |
| site_id | CSA21 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP32 | |
| site_id | CSA22 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP32 | |
| site_id | CSA23 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP32 | |
| site_id | CSA24 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP32 | |
| site_id | CSA25 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP228 | |
| site_id | CSA26 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP228 | |
| site_id | CSA27 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP228 | |
| site_id | CSA28 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP228 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | THR231 | |
| C | ASP228 | |
| C | SER35 | |
| C | ASP32 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | THR231 | |
| D | ASP228 | |
| D | SER35 | |
| D | ASP32 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP228 | |
| A | SER229 | |
| A | ASP32 | |
| A | THR33 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP228 | |
| B | SER229 | |
| B | ASP32 | |
| B | THR33 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP228 | |
| C | SER229 | |
| C | ASP32 | |
| C | THR33 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| D | ASP228 | |
| D | SER229 | |
| D | ASP32 | |
| D | THR33 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP228 | |
| A | SER35 | |
| A | ASP32 | |
