Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2VG3

Rv2361 with citronellyl pyrophosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004659	molecular_function	prenyltransferase activity
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0030145	molecular_function	manganese ion binding
A	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
A	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
A	0046872	molecular_function	metal ion binding
A	0052923	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity
B	0000287	molecular_function	magnesium ion binding
B	0004659	molecular_function	prenyltransferase activity
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0030145	molecular_function	manganese ion binding
B	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
B	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
B	0046872	molecular_function	metal ion binding
B	0052923	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity
C	0000287	molecular_function	magnesium ion binding
C	0004659	molecular_function	prenyltransferase activity
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
C	0016094	biological_process	polyprenol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0030145	molecular_function	manganese ion binding
C	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
C	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
C	0046872	molecular_function	metal ion binding
C	0052923	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity
D	0000287	molecular_function	magnesium ion binding
D	0004659	molecular_function	prenyltransferase activity
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
D	0016094	biological_process	polyprenol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0030145	molecular_function	manganese ion binding
D	0033850	molecular_function	Z-farnesyl diphosphate synthase activity
D	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
D	0046872	molecular_function	metal ion binding
D	0052923	molecular_function	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1297

Chain	Residue
A	ASP76
A	GPP1298
A	HOH2034
A	HOH2035
C	HOH2095

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GPP A 1298

Chain	Residue
A	GLY79
A	ARG80
A	ARG89
A	HIS93
A	GLY96
A	VAL100
A	ALA119
A	ARG127
A	MG1297
A	HOH2034
A	HOH2035
A	HOH2051
A	HOH2137
C	HOH2095
A	MET75
A	ASP76
A	GLY77
A	ASN78

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 A 1299

Chain	Residue
A	ARG244
A	ARG250
A	SER252
A	HOH2034
A	HOH2035
A	HOH2138
A	HOH2139
C	ARG292
C	PHE293
C	GLY294

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 1297

Chain	Residue
B	ASP76
B	GPP1298
B	HOH2027
B	HOH2104
B	HOH2105

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GPP B 1298

Chain	Residue
B	MET75
B	ASP76
B	GLY77
B	ASN78
B	GLY79
B	ARG80
B	ARG89
B	HIS93
B	ALA119
B	ASN124
B	ARG127
B	MG1297
B	HOH2104
B	HOH2105

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 B 1299

Chain	Residue
B	ARG244
B	ARG250
B	SER252
B	HOH2027
B	HOH2104
D	ARG292
D	PHE293
D	GLY294
D	HOH2079
D	HOH2080

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1297

Chain	Residue
C	ASP76
C	GPP1298
C	HOH2010
C	HOH2011
C	HOH2096

site_id	AC8
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GPP C 1298

Chain	Residue
A	ARG292
C	MET75
C	ASP76
C	GLY77
C	ASN78
C	GLY79
C	ARG80
C	ARG89
C	HIS93
C	ASN124
C	ARG127
C	MG1297
C	HOH2010
C	HOH2011
C	HOH2023
C	HOH2096
C	HOH2097
C	HOH2098

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 1297

Chain	Residue
D	ASP76
D	GPP1298
D	HOH2010
D	HOH2011
D	HOH2082

site_id	BC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GPP D 1298

Chain	Residue
D	HIS93
D	ALA119
D	ARG127
D	ASN139
D	TYR191
D	MG1297
D	HOH2010
D	HOH2011
D	HOH2024
D	HOH2081
D	HOH2082
A	HOH2057
B	ARG292
D	MET75
D	ASP76
D	GLY77
D	ASN78
D	GLY79
D	ARG80
D	ARG89

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 B 1300

Chain	Residue
A	ARG144
A	GLU173
B	ARG292
B	PHE293
B	HOH2106
D	HOH2081

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1301

Chain	Residue
A	SER169
B	ARG66
B	ARG291

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1302

Chain	Residue
A	ARG66
A	ARG291
B	ARG168
B	SER169

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1299

Chain	Residue
A	ASP21
A	HOH2002
C	ARG168
C	HOH2099

Functional Information from PROSITE/UniProt

site_id	PS01066
Number of Residues	18
Details	UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLFLRTSGeqRsSnFMLW

Chain	Residue	Details
A	ASP240-TRP257

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	20
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1f75

Chain	Residue	Details
A	ARG80
A	ARG244
A	ARG250
A	ARG89

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1f75

Chain	Residue	Details
B	ARG80
B	ARG244
B	ARG250
B	ARG89

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1f75

Chain	Residue	Details
C	ARG80
C	ARG244
C	ARG250
C	ARG89

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1f75

Chain	Residue	Details
D	ARG80
D	ARG244
D	ARG250
D	ARG89

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)