Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0020015 | cellular_component | glycosome |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0020015 | cellular_component | glycosome |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| C | 0004807 | molecular_function | triose-phosphate isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006094 | biological_process | gluconeogenesis |
| C | 0006096 | biological_process | glycolytic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0019563 | biological_process | glycerol catabolic process |
| C | 0020015 | cellular_component | glycosome |
| C | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A1251 |
| Chain | Residue |
| A | SER15 |
| C | GLY16 |
| C | HOH2064 |
| A | GLY16 |
| A | HOH2283 |
| A | HOH2284 |
| A | HOH2285 |
| A | HOH2286 |
| B | SER15 |
| B | GLY16 |
| C | SER15 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C1251 |
| Chain | Residue |
| C | LYS52 |
| C | VAL61 |
| C | ILE62 |
| C | ASN89 |
| C | HOH2077 |
| C | HOH2079 |
| C | HOH2238 |
| C | HOH2239 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A1252 |
| Chain | Residue |
| A | GLY16 |
| A | SER17 |
| A | HOH2287 |
| A | HOH2288 |
| A | HOH2289 |
| B | GLY16 |
| B | SER17 |
| B | HOH2018 |
| C | GLY16 |
| C | SER17 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1253 |
| Chain | Residue |
| A | ARG134 |
| A | GLN182 |
| A | HOH2220 |
| A | HOH2290 |
| A | HOH2291 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A1256 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1251 |
| Chain | Residue |
| B | THR105 |
| B | ASN106 |
| B | GLU107 |
| B | HOH2121 |
| B | HOH2228 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C1252 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C1253 |
| Chain | Residue |
| C | THR105 |
| C | ASN106 |
| C | GLU107 |
| C | HOH2120 |
| C | HOH2240 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C1254 |
| Chain | Residue |
| C | SER2 |
| C | LYS3 |
| C | HOH2241 |
| C | HOH2242 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C1255 |
| Chain | Residue |
| C | ARG134 |
| C | GLN182 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B1252 |
| Chain | Residue |
| B | SER2 |
| B | LYS3 |
| B | HOH2230 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B1253 |
| Chain | Residue |
| B | ARG134 |
| B | GLN182 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A1254 |
| Chain | Residue |
| A | LYS155 |
| A | LYS156 |
| A | HOH2292 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1254 |
| Chain | Residue |
| B | LYS13 |
| B | SER213 |
| B | GLY234 |
| B | LYS239 |
| B | HOH2231 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B1255 |
| Chain | Residue |
| B | THR44 |
| B | PHE45 |
| B | GLN65 |
| B | ASN66 |
| B | HOH2232 |
| B | HOH2233 |
| B | HOH2234 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1255 |
| Chain | Residue |
| A | ASN34 |
| A | LYS59 |
| A | HOH2294 |
| A | HOH2295 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA165-GLY175 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Electrophile"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| A | LYS13 | |
| A | HIS95 | |
| A | ASN11 | |
| A | GLU167 | |
| A | GLY173 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| B | LYS13 | |
| B | HIS95 | |
| B | ASN11 | |
| B | GLU167 | |
| B | GLY173 | |
| site_id | CSA3 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| C | LYS13 | |
| C | HIS95 | |
| C | ASN11 | |
| C | GLU167 | |
| C | GLY173 | |
