2VDV

Structure of trm8, m7G methylation enzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0006400	biological_process	tRNA modification
E	0008176	molecular_function	tRNA (guanine(46)-N7)-methyltransferase activity
F	0006400	biological_process	tRNA modification
F	0008176	molecular_function	tRNA (guanine(46)-N7)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE SAM E1287

Chain	Residue
E	GLY103
E	CYS181
E	PHE182
E	ASP184
E	THR259
E	GLU261
E	HOH2086
E	HOH2087
E	CYS104
E	GLY105
E	GLU126
E	ILE127
E	ARG128
E	GLY160
E	ASN161
E	ALA162

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site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE SAM F1287

Chain	Residue
F	GLY103
F	CYS104
F	GLU126
F	ILE127
F	ARG128
F	GLY160
F	ASN161
F	ALA162
F	CYS181
F	PHE182
F	ASP184
F	THR259
F	GLU261
F	HOH2116
F	HOH2117
F	HOH2119

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03055","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18184583","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

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