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2VCE

Characterization and engineering of the bifunctional N- and O- glucosyltransferase involved in xenobiotic metabolism in plants

Functional Information from GO Data
ChainGOidnamespacecontents
A0006805biological_processxenobiotic metabolic process
A0008194molecular_functionUDP-glycosyltransferase activity
A0009636biological_processresponse to toxic substance
A0009809biological_processlignin biosynthetic process
A0016757molecular_functionglycosyltransferase activity
A0035251molecular_functionUDP-glucosyltransferase activity
A0042178biological_processxenobiotic catabolic process
A0050505molecular_functionhydroquinone glucosyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues23
DetailsBINDING SITE FOR RESIDUE U2F A1477
ChainResidue
AGLY18
AHIS364
AGLY366
ATRP367
AASN368
ASER369
AGLU372
ATYR386
AALA387
AGLU388
AGLN389
AILE21
ATC71478
AHOH2008
AHOH2253
AHOH2402
APRO139
AGLY276
ASER277
AVAL303
ATRP346
AALA347
AGLN349

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE TC7 A1478
ChainResidue
AHIS19
AGLU83
ALEU118
APHE119
ALEU183
APRO185
ATYR315
AALA387
AGLU388
AU2F1477

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE EDO A1479
ChainResidue
APHE275
ATHR280
ALEU281
ALEU286
ATRP302
AVAL303
AILE304
AARG305
AHOH2403

Functional Information from PROSITE/UniProt
site_idPS00375
Number of Residues44
DetailsUDPGT UDP-glycosyltransferases signature. WapQaqVLahpstgGFLTHCGwnStleSVvsgi.PLiawPlyaEQ
ChainResidueDetails
ATRP346-GLN389

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:A0A0A1HA03
ChainResidueDetails
AHIS19

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Charge relay => ECO:0000250|UniProtKB:A0A0A1HA03
ChainResidueDetails
AASP117

site_idSWS_FT_FI3
Number of Residues11
DetailsBINDING: BINDING => ECO:0000305|PubMed:18077347, ECO:0007744|PDB:2VCE
ChainResidueDetails
ASER277
AGLU388
AGLN389
ATRP346
AALA347
AHIS364
ATRP367
AASN368
ASER369
AGLU372
ATYR386

227933

PDB entries from 2024-11-27

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