2V5H
Controlling the storage of nitrogen as arginine: the complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC 7942
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003991 | molecular_function | acetylglutamate kinase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006526 | biological_process | L-arginine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0003991 | molecular_function | acetylglutamate kinase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006526 | biological_process | L-arginine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0003991 | molecular_function | acetylglutamate kinase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006526 | biological_process | L-arginine biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0003991 | molecular_function | acetylglutamate kinase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006526 | biological_process | L-arginine biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0042802 | molecular_function | identical protein binding |
| E | 0003991 | molecular_function | acetylglutamate kinase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006526 | biological_process | L-arginine biosynthetic process |
| E | 0016301 | molecular_function | kinase activity |
| E | 0042802 | molecular_function | identical protein binding |
| F | 0003991 | molecular_function | acetylglutamate kinase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006526 | biological_process | L-arginine biosynthetic process |
| F | 0016301 | molecular_function | kinase activity |
| F | 0042802 | molecular_function | identical protein binding |
| G | 0005515 | molecular_function | protein binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005829 | cellular_component | cytosol |
| G | 0006808 | biological_process | regulation of nitrogen utilization |
| G | 0030234 | molecular_function | enzyme regulator activity |
| G | 0042802 | molecular_function | identical protein binding |
| H | 0005515 | molecular_function | protein binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005829 | cellular_component | cytosol |
| H | 0006808 | biological_process | regulation of nitrogen utilization |
| H | 0030234 | molecular_function | enzyme regulator activity |
| H | 0042802 | molecular_function | identical protein binding |
| I | 0005515 | molecular_function | protein binding |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005829 | cellular_component | cytosol |
| I | 0006808 | biological_process | regulation of nitrogen utilization |
| I | 0030234 | molecular_function | enzyme regulator activity |
| I | 0042802 | molecular_function | identical protein binding |
| J | 0005515 | molecular_function | protein binding |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005829 | cellular_component | cytosol |
| J | 0006808 | biological_process | regulation of nitrogen utilization |
| J | 0030234 | molecular_function | enzyme regulator activity |
| J | 0042802 | molecular_function | identical protein binding |
| K | 0005515 | molecular_function | protein binding |
| K | 0005524 | molecular_function | ATP binding |
| K | 0005829 | cellular_component | cytosol |
| K | 0006808 | biological_process | regulation of nitrogen utilization |
| K | 0030234 | molecular_function | enzyme regulator activity |
| K | 0042802 | molecular_function | identical protein binding |
| L | 0005515 | molecular_function | protein binding |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005829 | cellular_component | cytosol |
| L | 0006808 | biological_process | regulation of nitrogen utilization |
| L | 0030234 | molecular_function | enzyme regulator activity |
| L | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NLG A 1292 |
| Chain | Residue |
| A | GLY69 |
| A | ALA188 |
| A | GLY70 |
| A | GLY71 |
| A | ILE74 |
| A | ARG92 |
| A | SER174 |
| A | ASN185 |
| A | ILE186 |
| A | ASN187 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1293 |
| Chain | Residue |
| A | GLU277 |
| A | THR280 |
| A | HOH2027 |
| A | HOH2028 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NLG B 1297 |
| Chain | Residue |
| B | GLY69 |
| B | GLY70 |
| B | GLY71 |
| B | ILE74 |
| B | ARG92 |
| B | SER174 |
| B | ASN185 |
| B | ILE186 |
| B | ALA188 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 1298 |
| Chain | Residue |
| B | GLU277 |
| B | THR280 |
| B | HOH2022 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NLG C 1292 |
| Chain | Residue |
| C | GLY69 |
| C | GLY70 |
| C | GLY71 |
| C | ILE74 |
| C | ARG92 |
| C | SER174 |
| C | ASN185 |
| C | ALA188 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 1293 |
| Chain | Residue |
| C | GLU277 |
| C | THR280 |
| C | HOH2014 |
| C | HOH2015 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NLG D 1294 |
| Chain | Residue |
| D | GLY69 |
| D | GLY70 |
| D | GLY71 |
| D | ILE74 |
| D | ARG92 |
| D | ASN185 |
| D | ALA188 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA D 1295 |
| Chain | Residue |
| D | GLU277 |
| D | THR280 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NLG E 1294 |
| Chain | Residue |
| E | GLY69 |
| E | GLY70 |
| E | GLY71 |
| E | ILE74 |
| E | ARG92 |
| E | ASN185 |
| E | ALA188 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 1295 |
| Chain | Residue |
| D | GLY181 |
| E | LYS112 |
| E | ASP113 |
| E | ARG117 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA E 1296 |
| Chain | Residue |
| E | GLU277 |
| E | THR280 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NLG F 1293 |
| Chain | Residue |
| F | GLY69 |
| F | GLY70 |
| F | GLY71 |
| F | ARG92 |
| F | VAL149 |
| F | ASN185 |
| F | ALA188 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA F 1294 |
| Chain | Residue |
| F | GLU277 |
| F | THR280 |
| F | HOH2022 |
| F | HOH2023 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL G 1112 |
| Chain | Residue |
| G | GLN39 |
| G | GLY87 |
| G | ASP88 |
| I | ARG103 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL H 1109 |
| Chain | Residue |
| G | ARG103 |
| H | ILE86 |
| H | GLY87 |
| H | HOH2011 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL H 1110 |
| Chain | Residue |
| H | ARG101 |
| H | ARG103 |
| I | ILE86 |
| I | GLY87 |
| I | ASP88 |
| I | HOH2008 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL J 1111 |
| Chain | Residue |
| J | ARG103 |
| K | ILE86 |
| K | GLY87 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL J 1112 |
| Chain | Residue |
| J | ILE86 |
| J | GLY87 |
| L | ARG103 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL K 1109 |
| Chain | Residue |
| K | ARG101 |
| K | ARG103 |
| L | GLY87 |
| L | ASP88 |
| L | HOH2010 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00082","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"7592328","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"O-UMP-tyrosine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00675","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| A | GLY38 | |
| A | LYS35 | |
| A | LYS248 | |
| A | GLY71 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| B | GLY38 | |
| B | LYS35 | |
| B | LYS248 | |
| B | GLY71 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| C | GLY38 | |
| C | LYS35 | |
| C | LYS248 | |
| C | GLY71 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| D | GLY38 | |
| D | LYS35 | |
| D | LYS248 | |
| D | GLY71 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| E | GLY38 | |
| E | LYS35 | |
| E | LYS248 | |
| E | GLY71 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1oh9 |
| Chain | Residue | Details |
| F | GLY38 | |
| F | LYS35 | |
| F | LYS248 | |
| F | GLY71 |
