Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| O | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| O | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C80 C1341 |
| Chain | Residue |
| C | THR18 |
| C | ALA122 |
| C | PHE124 |
| C | GLN135 |
| C | ASP226 |
| C | THR227 |
| C | GLY228 |
| C | ALA229 |
| C | SER230 |
| C | TYR20 |
| C | VAL36 |
| C | ASP38 |
| C | SER41 |
| C | SER42 |
| C | TYR83 |
| C | SER84 |
| C | THR85 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE C80 O1341 |
| Chain | Residue |
| O | THR18 |
| O | GLN19 |
| O | TYR20 |
| O | VAL36 |
| O | ASP38 |
| O | GLY40 |
| O | SER41 |
| O | ARG82 |
| O | TYR83 |
| O | SER84 |
| O | THR85 |
| O | PRO118 |
| O | LEU121 |
| O | ALA122 |
| O | GLN135 |
| O | ILE137 |
| O | ASP226 |
| O | THR227 |
| O | GLY228 |
| O | ALA229 |
| O | SER230 |
| O | ILE305 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVFDTGSSNVWV |
| Chain | Residue | Details |
| C | VAL35-VAL46 | |
| C | ALA223-GLY234 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"20927107","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"2493678","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| C | ASP38 | |
| C | ASP226 | |
| C | THR39 | |
| C | THR227 | |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| O | ASP226 | |
| O | THR32 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| O | ASP38 | |
| O | ASP226 | |
| O | THR39 | |
| O | THR227 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| C | ASP38 | |
| C | ASP226 | |
| C | SER41 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| O | ASP38 | |
| O | ASP226 | |
| O | SER41 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| C | ASP38 | |
| C | ASP226 | |
| C | TYR83 | |
| C | SER41 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| O | ASP38 | |
| O | ASP226 | |
| O | TYR83 | |
| O | SER41 | |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| C | ASP38 | |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| O | ASP38 | |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1avf |
| Chain | Residue | Details |
| C | ASP226 | |
| C | THR32 | |
