2V06
Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis at pH 5.5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004722 | molecular_function | protein serine/threonine phosphatase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0032873 | biological_process | negative regulation of stress-activated MAPK cascade |
| A | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| A | 0043124 | biological_process | negative regulation of canonical NF-kappaB signal transduction |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090263 | biological_process | positive regulation of canonical Wnt signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1234 |
| Chain | Residue |
| A | ASP35 |
| A | ASP185 |
| A | ASP223 |
| A | HOH2322 |
| A | HOH2379 |
| A | HOH2381 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1235 |
| Chain | Residue |
| A | HOH2070 |
| A | HOH2098 |
| A | HOH2379 |
| A | ASP35 |
| A | GLY36 |
| A | HOH2063 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1237 |
| Chain | Residue |
| A | HOH2163 |
| A | HOH2164 |
| A | HOH2336 |
| A | HOH2342 |
| A | HOH2343 |
| A | HOH2357 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A1236 |
| Chain | Residue |
| A | HOH2380 |
