2UZZ
X-ray structure of N-methyl-L-tryptophan oxidase (MTOX)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008115 | molecular_function | sarcosine oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016647 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor |
| A | 0050131 | molecular_function | N-methyl-L-amino-acid oxidase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008115 | molecular_function | sarcosine oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016647 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor |
| B | 0050131 | molecular_function | N-methyl-L-amino-acid oxidase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008115 | molecular_function | sarcosine oxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016647 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor |
| C | 0050131 | molecular_function | N-methyl-L-amino-acid oxidase activity |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008115 | molecular_function | sarcosine oxidase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016647 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor |
| D | 0050131 | molecular_function | N-methyl-L-amino-acid oxidase activity |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FAD A 1373 |
| Chain | Residue |
| A | GLY9 |
| A | HIS43 |
| A | ARG48 |
| A | LEU49 |
| A | VAL172 |
| A | CYS199 |
| A | ALA200 |
| A | GLY201 |
| A | LEU207 |
| A | PHE220 |
| A | TYR249 |
| A | GLY11 |
| A | CYS308 |
| A | THR309 |
| A | TYR310 |
| A | LEU335 |
| A | GLY337 |
| A | GLY339 |
| A | PHE340 |
| A | LYS341 |
| A | NA1374 |
| A | SER12 |
| A | VAL13 |
| A | ASP32 |
| A | ALA33 |
| A | HIS38 |
| A | GLY41 |
| A | SER42 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1374 |
| Chain | Residue |
| A | ASP311 |
| A | LEU335 |
| A | GLY337 |
| A | FAD1373 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD B 1373 |
| Chain | Residue |
| B | ILE8 |
| B | GLY9 |
| B | GLY11 |
| B | SER12 |
| B | VAL13 |
| B | ASP32 |
| B | ALA33 |
| B | HIS34 |
| B | HIS38 |
| B | GLY41 |
| B | SER42 |
| B | HIS43 |
| B | ARG48 |
| B | LEU49 |
| B | VAL172 |
| B | CYS199 |
| B | ALA200 |
| B | GLY201 |
| B | PHE220 |
| B | TYR249 |
| B | CYS308 |
| B | THR309 |
| B | TYR310 |
| B | LEU335 |
| B | GLY337 |
| B | GLY339 |
| B | PHE340 |
| B | LYS341 |
| B | NA1374 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1374 |
| Chain | Residue |
| B | ASP311 |
| B | LEU335 |
| B | GLY337 |
| B | FAD1373 |
| site_id | AC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD C 1371 |
| Chain | Residue |
| C | ILE8 |
| C | GLY9 |
| C | GLY11 |
| C | SER12 |
| C | VAL13 |
| C | ASP32 |
| C | ALA33 |
| C | HIS38 |
| C | GLY41 |
| C | SER42 |
| C | HIS43 |
| C | ARG48 |
| C | LEU49 |
| C | VAL172 |
| C | CYS199 |
| C | ALA200 |
| C | GLY201 |
| C | LEU207 |
| C | PHE220 |
| C | TYR249 |
| C | CYS308 |
| C | THR309 |
| C | TYR310 |
| C | LEU335 |
| C | GLY337 |
| C | GLY339 |
| C | PHE340 |
| C | LYS341 |
| C | NA1372 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA C 1372 |
| Chain | Residue |
| C | THR309 |
| C | ASP311 |
| C | LEU335 |
| C | FAD1371 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD D 1372 |
| Chain | Residue |
| D | GLY9 |
| D | GLY11 |
| D | SER12 |
| D | VAL13 |
| D | ASP32 |
| D | ALA33 |
| D | HIS34 |
| D | HIS38 |
| D | GLY41 |
| D | SER42 |
| D | HIS43 |
| D | ARG48 |
| D | LEU49 |
| D | VAL172 |
| D | CYS199 |
| D | ALA200 |
| D | GLY201 |
| D | PHE220 |
| D | TYR249 |
| D | CYS308 |
| D | THR309 |
| D | TYR310 |
| D | LEU335 |
| D | GLY337 |
| D | GLY339 |
| D | PHE340 |
| D | LYS341 |
| D | NA1373 |
| D | ILE8 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA D 1373 |
| Chain | Residue |
| D | TYR310 |
| D | ASP311 |
| D | LEU335 |
| D | GLY337 |
| D | FAD1372 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP4 | |
| B | ASP4 | |
| C | ASP4 | |
| D | ASP4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: S-8alpha-FAD cysteine |
| Chain | Residue | Details |
| A | CYS308 | |
| B | CYS308 | |
| C | CYS308 | |
| D | CYS308 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| A | GLY337 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| B | GLY337 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| C | GLY337 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| D | GLY337 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| A | HIS44 | |
| A | ARG48 | |
| A | HIS263 | |
| A | CYS308 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| B | HIS44 | |
| B | ARG48 | |
| B | HIS263 | |
| B | CYS308 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| C | HIS44 | |
| C | ARG48 | |
| C | HIS263 | |
| C | CYS308 |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2gb0 |
| Chain | Residue | Details |
| D | HIS44 | |
| D | ARG48 | |
| D | HIS263 | |
| D | CYS308 |
