2UYZ
Non-covalent complex between Ubc9 and SUMO1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000122 | biological_process | negative regulation of transcription by RNA polymerase II |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001650 | cellular_component | fibrillar center |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005643 | cellular_component | nuclear pore |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0007049 | biological_process | cell cycle |
| A | 0007059 | biological_process | chromosome segregation |
| A | 0016604 | cellular_component | nuclear body |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016925 | biological_process | protein sumoylation |
| A | 0019789 | molecular_function | SUMO transferase activity |
| A | 0030425 | cellular_component | dendrite |
| A | 0035255 | molecular_function | ionotropic glutamate receptor binding |
| A | 0036211 | biological_process | protein modification process |
| A | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
| A | 0043398 | molecular_function | HLH domain binding |
| A | 0043425 | molecular_function | bHLH transcription factor binding |
| A | 0051168 | biological_process | nuclear export |
| A | 0051301 | biological_process | cell division |
| A | 0061656 | molecular_function | SUMO conjugating enzyme activity |
| A | 0106068 | cellular_component | SUMO ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A1159 |
| Chain | Residue |
| A | TYR87 |
| A | SER93 |
| A | GLU98 |
| A | HOH2140 |
| A | HOH2154 |
| A | HOH2157 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388 |
| Chain | Residue | Details |
| A | SER93 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Interaction with RANBP2 => ECO:0000250 |
| Chain | Residue | Details |
| A | VAL25 | |
| A | LEU57 | |
| A | ILE4 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Substrate binding => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP100 | |
| B | LYS39 | |
| B | LYS45 | |
| B | LYS46 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | SER2 | |
| B | GLY97 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | LYS65 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by CDK1 => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | SER71 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | LYS18 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | LYS48 | |
| A | LYS101 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P63279 |
| Chain | Residue | Details |
| A | LYS49 |
