2UYV
L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT Q6Y- E192A)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005996 | biological_process | monosaccharide metabolic process |
| A | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016830 | molecular_function | carbon-carbon lyase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| A | 0019299 | biological_process | rhamnose metabolic process |
| A | 0019301 | biological_process | rhamnose catabolic process |
| A | 0019323 | biological_process | pentose catabolic process |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005996 | biological_process | monosaccharide metabolic process |
| B | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016830 | molecular_function | carbon-carbon lyase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0019299 | biological_process | rhamnose metabolic process |
| B | 0019301 | biological_process | rhamnose catabolic process |
| B | 0019323 | biological_process | pentose catabolic process |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0005996 | biological_process | monosaccharide metabolic process |
| C | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016830 | molecular_function | carbon-carbon lyase activity |
| C | 0016832 | molecular_function | aldehyde-lyase activity |
| C | 0019299 | biological_process | rhamnose metabolic process |
| C | 0019301 | biological_process | rhamnose catabolic process |
| C | 0019323 | biological_process | pentose catabolic process |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0005996 | biological_process | monosaccharide metabolic process |
| D | 0008994 | molecular_function | rhamnulose-1-phosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016830 | molecular_function | carbon-carbon lyase activity |
| D | 0016832 | molecular_function | aldehyde-lyase activity |
| D | 0019299 | biological_process | rhamnose metabolic process |
| D | 0019301 | biological_process | rhamnose catabolic process |
| D | 0019323 | biological_process | pentose catabolic process |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TLA A1275 |
| Chain | Residue |
| A | ASN29 |
| A | ZN1276 |
| A | TLA1277 |
| A | HOH2123 |
| A | HOH2162 |
| A | HOH2253 |
| A | GLY30 |
| A | GLY31 |
| A | ASN32 |
| A | SER75 |
| A | GLY76 |
| A | THR115 |
| A | SER116 |
| A | GLU117 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE TLA B1275 |
| Chain | Residue |
| B | ASN29 |
| B | GLY30 |
| B | GLY31 |
| B | ASN32 |
| B | THR115 |
| B | SER116 |
| B | GLU117 |
| B | HIS141 |
| B | HIS143 |
| B | HIS212 |
| B | ZN1276 |
| B | HOH2094 |
| B | HOH2099 |
| B | HOH2259 |
| B | HOH2260 |
| B | HOH2261 |
| B | HOH2262 |
| B | HOH2263 |
| B | HOH2264 |
| B | HOH2266 |
| C | GLU171 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE TLA C1275 |
| Chain | Residue |
| C | ASN29 |
| C | GLY30 |
| C | GLY31 |
| C | ASN32 |
| C | THR115 |
| C | SER116 |
| C | HIS141 |
| C | HIS143 |
| C | HIS212 |
| C | ZN1276 |
| C | HOH2048 |
| C | HOH2053 |
| C | HOH2119 |
| C | HOH2232 |
| D | GLU171 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TLA D1275 |
| Chain | Residue |
| D | ASN29 |
| D | GLY30 |
| D | GLY31 |
| D | ASN32 |
| D | SER75 |
| D | GLY76 |
| D | THR115 |
| D | SER116 |
| D | GLU117 |
| D | HIS141 |
| D | HIS143 |
| D | ZN1276 |
| D | HOH2222 |
| D | HOH2224 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A1276 |
| Chain | Residue |
| A | HIS141 |
| A | HIS143 |
| A | HIS212 |
| A | TLA1275 |
| A | TLA1277 |
| A | HOH2253 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B1276 |
| Chain | Residue |
| B | HIS141 |
| B | HIS143 |
| B | HIS212 |
| B | TLA1275 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C1276 |
| Chain | Residue |
| C | HIS141 |
| C | HIS143 |
| C | HIS212 |
| C | TLA1275 |
| D | GLU171 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D1276 |
| Chain | Residue |
| D | HIS141 |
| D | HIS143 |
| D | HIS212 |
| D | TLA1275 |
| D | HOH2222 |
| D | HOH2224 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE TLA A1277 |
| Chain | Residue |
| A | GLU117 |
| A | HIS143 |
| A | PRO188 |
| A | GLY189 |
| A | HIS212 |
| A | TLA1275 |
| A | ZN1276 |
| A | HOH2164 |
| A | HOH2253 |
| B | GLU171 |
| B | PHE263 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479 |
| Chain | Residue | Details |
| A | GLU117 | |
| B | GLU117 | |
| C | GLU117 | |
| D | GLU117 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11976494, ECO:0000269|PubMed:12962479 |
| Chain | Residue | Details |
| A | HIS141 | |
| D | HIS141 | |
| D | HIS143 | |
| D | HIS212 | |
| A | HIS143 | |
| A | HIS212 | |
| B | HIS141 | |
| B | HIS143 | |
| B | HIS212 | |
| C | HIS141 | |
| C | HIS143 | |
| C | HIS212 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| A | GLU117 | |
| A | GLU171 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| B | GLU117 | |
| B | GLU171 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| C | GLU117 | |
| C | GLU171 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| D | GLU117 | |
| D | GLU171 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| A | VAL174 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| B | VAL174 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| C | VAL174 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1gt7 |
| Chain | Residue | Details |
| D | VAL174 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| A | GLU117 | proton acceptor, proton donor |
| A | HIS141 | metal ligand |
| A | HIS143 | metal ligand |
| A | GLU171 | proton donor |
| A | HIS212 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| B | GLU117 | proton acceptor, proton donor |
| B | HIS141 | metal ligand |
| B | HIS143 | metal ligand |
| B | GLU171 | proton donor |
| B | HIS212 | metal ligand |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| C | GLU117 | proton acceptor, proton donor |
| C | HIS141 | metal ligand |
| C | HIS143 | metal ligand |
| C | GLU171 | proton donor |
| C | HIS212 | metal ligand |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 645 |
| Chain | Residue | Details |
| D | GLU117 | proton acceptor, proton donor |
| D | HIS141 | metal ligand |
| D | HIS143 | metal ligand |
| D | GLU171 | proton donor |
| D | HIS212 | metal ligand |
