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2RJF

Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
C0005634cellular_componentnucleus
C0006355biological_processregulation of DNA-templated transcription
E0005634cellular_componentnucleus
E0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
BGLY14-HIS18

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsSITE: Mediates recognition of monomethylated and dimethylated peptides
ChainResidueDetails
ACYS423
CCYS423
ECYS423

site_idSWS_FT_FI2
Number of Residues3
DetailsSITE: Positioned at the entrance of MBT 2 and is required for recognition of monomethylated and dimethylated peptides
ChainResidueDetails
ALYS426
CLYS426
ELYS426

226707

PDB entries from 2024-10-30

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