2RIW

The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005615	cellular_component	extracellular space

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE T44 A1395

Chain	Residue
A	SER23
A	HOH1659
B	LEU376
B	ARG378
A	GLN238
A	LEU246
A	LEU269
A	LYS270
A	ASN273
A	HOH1454
A	HOH1478
A	HOH1605

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Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. IQIDRSFMLlI

Chain	Residue	Details
B	ILE365-ILE375

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16938877

Chain	Residue	Details
B	ARG378

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
A	ASN79
A	ASN233

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in variant Gary => ECO:0000305

Chain	Residue	Details
A	ILE96

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952

Chain	Residue	Details
A	ASN145

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