2RFB
Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
B | 0004497 | molecular_function | monooxygenase activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
B | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
B | 0020037 | molecular_function | heme binding |
B | 0046872 | molecular_function | metal ion binding |
C | 0004497 | molecular_function | monooxygenase activity |
C | 0005506 | molecular_function | iron ion binding |
C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
C | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
C | 0020037 | molecular_function | heme binding |
C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 900 |
Chain | Residue |
A | ASP99 |
A | PHE325 |
A | LYS326 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 910 |
Chain | Residue |
A | PHE280 |
A | ASP281 |
A | ARG290 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 920 |
Chain | Residue |
A | ILE54 |
A | SER55 |
A | LYS189 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 C 910 |
Chain | Residue |
C | PHE280 |
C | ASP281 |
C | ARG290 |
C | ARG291 |
C | HOH931 |
site_id | AC5 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE HEM A 410 |
Chain | Residue |
A | PHE56 |
A | ILE57 |
A | HIS64 |
A | ARG68 |
A | LEU194 |
A | GLY197 |
A | GLY198 |
A | THR201 |
A | ILE241 |
A | ARG247 |
A | LEU270 |
A | ALA296 |
A | PHE297 |
A | GLY298 |
A | ILE301 |
A | HIS302 |
A | CYS304 |
A | GLY306 |
A | HOH944 |
A | HOH946 |
site_id | AC6 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE HEM B 410 |
Chain | Residue |
B | PHE56 |
B | ILE57 |
B | HIS64 |
B | ARG68 |
B | PHE75 |
B | LEU193 |
B | LEU194 |
B | GLY197 |
B | GLY198 |
B | THR201 |
B | HIS246 |
B | ARG247 |
B | LEU270 |
B | ALA296 |
B | PHE297 |
B | GLY298 |
B | ILE301 |
B | HIS302 |
B | CYS304 |
B | GLY306 |
B | LEU309 |
B | ALA310 |
B | HOH412 |
B | HOH419 |
B | HOH420 |
site_id | AC7 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE HEM C 410 |
Chain | Residue |
C | PHE56 |
C | ILE57 |
C | HIS64 |
C | ARG68 |
C | LEU194 |
C | GLY197 |
C | GLY198 |
C | THR201 |
C | LEU205 |
C | LEU235 |
C | LEU244 |
C | ARG247 |
C | ALA296 |
C | PHE297 |
C | GLY298 |
C | ILE301 |
C | HIS302 |
C | CYS304 |
C | GLY306 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGiGIHMCLG |
Chain | Residue | Details |
A | PHE297-GLY306 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
A | THR201 | |
A | GLU200 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
B | THR201 | |
B | GLU200 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1akd |
Chain | Residue | Details |
C | THR201 | |
C | GLU200 |