2RB3

Crystal Structure of Human Saposin D

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005764	cellular_component	lysosome
A	0006629	biological_process	lipid metabolic process
A	0006665	biological_process	sphingolipid metabolic process
B	0005764	cellular_component	lysosome
B	0006629	biological_process	lipid metabolic process
B	0006665	biological_process	sphingolipid metabolic process
C	0005764	cellular_component	lysosome
C	0006629	biological_process	lipid metabolic process
C	0006665	biological_process	sphingolipid metabolic process
D	0005764	cellular_component	lysosome
D	0006629	biological_process	lipid metabolic process
D	0006665	biological_process	sphingolipid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 100

Chain	Residue
A	ARG17
A	HOH133
A	HOH134
A	HOH183
A	HOH199

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 101

Chain	Residue
B	ARG17
A	TYR14
A	ARG17
A	ASN18
A	HOH188

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 100

Chain	Residue
C	LYS10
C	ARG17
C	HOH122
C	HOH124
C	HOH181

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 200

Chain	Residue
B	ARG17
B	PRO68
B	HOH226
B	HOH240

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL D 200

Chain	Residue
C	GLU64
D	ALA52
D	HOH285

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00415","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19167329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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