Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0003824 | molecular_function | catalytic activity |
A | 0004802 | molecular_function | transketolase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006098 | biological_process | pentose-phosphate shunt |
A | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
A | 0016740 | molecular_function | transferase activity |
A | 0016744 | molecular_function | transketolase or transaldolase activity |
A | 0030145 | molecular_function | manganese ion binding |
A | 0030976 | molecular_function | thiamine pyrophosphate binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0004802 | molecular_function | transketolase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006098 | biological_process | pentose-phosphate shunt |
B | 0009052 | biological_process | pentose-phosphate shunt, non-oxidative branch |
B | 0016740 | molecular_function | transferase activity |
B | 0016744 | molecular_function | transketolase or transaldolase activity |
B | 0030145 | molecular_function | manganese ion binding |
B | 0030976 | molecular_function | thiamine pyrophosphate binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA A 670 |
Chain | Residue |
A | ASP155 |
A | ASN185 |
A | ILE187 |
A | T5X671 |
A | HOH680 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 670 |
Chain | Residue |
B | HOH730 |
B | ASP155 |
B | ASN185 |
B | ILE187 |
B | T5X671 |
site_id | AC3 |
Number of Residues | 36 |
Details | BINDING SITE FOR RESIDUE T5X A 671 |
Chain | Residue |
A | HIS26 |
A | ALA29 |
A | HIS66 |
A | HIS100 |
A | GLY114 |
A | LEU116 |
A | ASP155 |
A | GLY156 |
A | GLU160 |
A | ASN185 |
A | ILE187 |
A | ILE189 |
A | ILE247 |
A | HIS261 |
A | CA670 |
A | HOH677 |
A | HOH680 |
A | HOH681 |
A | HOH682 |
A | HOH687 |
A | HOH691 |
A | HOH697 |
A | HOH703 |
A | HOH747 |
A | HOH793 |
B | ASP381 |
B | SER385 |
B | GLU411 |
B | PHE434 |
B | PHE437 |
B | TYR440 |
B | HIS461 |
B | ASP469 |
B | HIS473 |
B | ARG520 |
B | HOH1232 |
site_id | AC4 |
Number of Residues | 35 |
Details | BINDING SITE FOR RESIDUE T5X B 671 |
Chain | Residue |
A | ASP381 |
A | SER385 |
A | GLU411 |
A | PHE434 |
A | PHE437 |
A | TYR440 |
A | HIS461 |
A | ASP469 |
A | HIS473 |
A | ARG520 |
A | HOH700 |
A | HOH943 |
B | HIS26 |
B | ALA29 |
B | HIS66 |
B | HIS100 |
B | GLY114 |
B | LEU116 |
B | ASP155 |
B | GLY156 |
B | GLU160 |
B | ASN185 |
B | ILE187 |
B | ILE189 |
B | ILE247 |
B | HIS261 |
B | CA670 |
B | HOH682 |
B | HOH690 |
B | HOH693 |
B | HOH695 |
B | HOH699 |
B | HOH736 |
B | HOH763 |
B | HOH1252 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 672 |
Chain | Residue |
B | GLU6 |
B | GLY278 |
B | TRP279 |
B | LYS280 |
B | TYR281 |
B | HOH913 |
B | HOH1215 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 673 |
Chain | Residue |
B | ALA271 |
B | TYR505 |
B | GLU508 |
B | ARG509 |
B | HOH783 |
B | HOH816 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 674 |
Chain | Residue |
B | HOH1124 |
B | HOH1224 |
B | ARG274 |
B | GLU275 |
B | TRP279 |
B | GLN592 |
B | HOH822 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 675 |
Chain | Residue |
B | LEU272 |
B | GLU275 |
B | ARG509 |
B | ASP511 |
B | HOH1103 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 676 |
Chain | Residue |
B | PHE375 |
B | TRP390 |
B | SER393 |
B | ASN403 |
B | TYR404 |
B | TYR430 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 677 |
Chain | Residue |
B | PRO52 |
B | GLY108 |
B | VAL109 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 672 |
Chain | Residue |
A | ILE615 |
A | ASP617 |
A | THR633 |
A | HOH898 |
B | ARG483 |
B | HOH906 |
site_id | BC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 678 |
Chain | Residue |
B | SER559 |
B | GLU560 |
B | PHE645 |
B | PHE650 |
B | HOH917 |
B | HOH1088 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 679 |
Chain | Residue |
B | LYS131 |
B | THR172 |
B | LYS174 |
B | ASN397 |
B | HOH842 |
B | HOH1094 |
site_id | BC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO B 680 |
Chain | Residue |
B | LEU435 |
B | ASP462 |
B | PRO475 |
B | VAL479 |
B | ARG492 |
B | ALA613 |
B | GLY614 |
B | HOH752 |
site_id | BC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 681 |
Chain | Residue |
B | PHE325 |
B | THR326 |
B | HOH881 |
Functional Information from PROSITE/UniProt
site_id | PS00801 |
Number of Residues | 21 |
Details | TRANSKETOLASE_1 Transketolase signature 1. RalsMDavqkakSGHPGapMG |
Chain | Residue | Details |
A | ARG12-GLY32 | |
site_id | PS00802 |
Number of Residues | 17 |
Details | TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHqPVEqvAslR |
Chain | Residue | Details |
A | GLY467-ARG483 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000305 |
Chain | Residue | Details |
A | GLU411 | |
B | GLU411 | |
Chain | Residue | Details |
A | HIS26 | |
B | SER385 | |
B | HIS461 | |
B | ASP469 | |
B | HIS473 | |
B | ARG520 | |
A | ARG358 | |
A | SER385 | |
A | HIS461 | |
A | ASP469 | |
A | HIS473 | |
A | ARG520 | |
B | HIS26 | |
B | ARG358 | |
Chain | Residue | Details |
A | HIS66 | |
A | GLY114 | |
A | ASN185 | |
A | HIS261 | |
B | HIS66 | |
B | GLY114 | |
B | ASN185 | |
B | HIS261 | |
Chain | Residue | Details |
A | ASP155 | |
A | ILE187 | |
B | ASP155 | |
B | ILE187 | |
Chain | Residue | Details |
A | GLY156 | |
B | GLY156 | |
Chain | Residue | Details |
A | PHE437 | |
B | PHE437 | |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | SITE: Important for catalytic activity |
Chain | Residue | Details |
A | HIS26 | |
A | HIS261 | |
B | HIS26 | |
B | HIS261 | |
Chain | Residue | Details |
A | LYS46 | |
B | LYS46 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | SER251 | |
site_id | CSA10 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | HIS261 | |
B | HIS26 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | SER251 | |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | GLU411 | |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | GLU411 | |
site_id | CSA5 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | PRO252 | |
site_id | CSA6 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | PRO252 | |
site_id | CSA7 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS258 | |
site_id | CSA8 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
B | HIS258 | |
site_id | CSA9 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dtw |
Chain | Residue | Details |
A | HIS261 | |
A | HIS26 | |