2R8F

Crystal structure of H225A NSP2 and ATP-gS complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003723	molecular_function	RNA binding
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0016787	molecular_function	hydrolase activity
A	0016817	molecular_function	hydrolase activity, acting on acid anhydrides
A	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
A	0019079	biological_process	viral genome replication
A	0030430	cellular_component	host cell cytoplasm
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 318

Chain	Residue
A	ARG210
A	LYS301
A	GLY302
A	LEU303
A	SER304
A	HOH499

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE AGS A 400

Chain	Residue
A	LYS223
A	ARG227
A	ARG240
A	THR244
A	HOH412
A	HOH413
A	HOH416
A	HOH490
A	HOH494
A	HOH495
A	ARG109
A	LYS188
A	HIS221

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: For NTPase and RTPase activities => ECO:0000255|HAMAP-Rule:MF_04089, ECO:0000305|PubMed:17804496

Chain	Residue	Details
A	ALA225

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04089, ECO:0007744|PDB:2R7P

Chain	Residue	Details
A	SER107
A	LYS188
A	HIS221
A	ARG227

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