2R7P
Crystal Structure of H225A NSP2 and AMPPNP complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004550 | molecular_function | nucleoside diphosphate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016817 | molecular_function | hydrolase activity, acting on acid anhydrides |
| A | 0017111 | molecular_function | ribonucleoside triphosphate phosphatase activity |
| A | 0019079 | biological_process | viral genome replication |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 318 |
| Chain | Residue |
| A | ARG210 |
| A | LYS301 |
| A | GLY302 |
| A | LEU303 |
| A | SER304 |
| A | THR305 |
| A | HOH447 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ANP A 400 |
| Chain | Residue |
| A | LYS188 |
| A | HIS221 |
| A | LYS223 |
| A | ARG227 |
| A | HOH401 |
| A | HOH402 |
| A | HOH404 |
| A | HOH405 |
| A | HOH406 |
| A | SER107 |
| A | ARG109 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Region: {"description":"RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22811529","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For NTPase and RTPase activities","evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17804496","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"2R7P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
