2R7C
Crystallographic and biochemical analysis of rotavirus NSP2 with nucleotides reveals an NDP kinase like activity
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0003723 | molecular_function | RNA binding |
A | 0004550 | molecular_function | nucleoside diphosphate kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016817 | molecular_function | hydrolase activity, acting on acid anhydrides |
A | 0017111 | molecular_function | ribonucleoside triphosphate phosphatase activity |
A | 0019079 | biological_process | viral genome replication |
A | 0030430 | cellular_component | host cell cytoplasm |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: For NTPase and RTPase activities => ECO:0000255|HAMAP-Rule:MF_04089, ECO:0000305|PubMed:17804496 |
Chain | Residue | Details |
A | PSH225 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04089, ECO:0007744|PDB:2R7P |
Chain | Residue | Details |
A | SER107 | |
A | LYS188 | |
A | HIS221 | |
A | ARG227 |