2R0V

Structure of the Rsc4 tandem bromodomain acetylated at K25

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006338	biological_process	chromatin remodeling
A	0016586	cellular_component	RSC-type complex
B	0006338	biological_process	chromatin remodeling
B	0016586	cellular_component	RSC-type complex
C	0006338	biological_process	chromatin remodeling
C	0016586	cellular_component	RSC-type complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 341

Chain	Residue
A	HIS177
A	ASN180
A	ARG303
A	HOH399
A	HOH468
B	HOH455

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 342

Chain	Residue
A	HIS177
A	LYS181

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 343

Chain	Residue
A	TYR251
A	ILE254
A	ASN286
A	ILE289
A	GLN290
A	HOH480
A	GLU47

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 341

Chain	Residue
C	HIS89
C	PRO90
C	GLN91
C	TYR92
C	TYR133

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 342

Chain	Residue
C	ALY25
C	HIS89

---

Functional Information from PROSITE/UniProt

site_id	PS00633
Number of Residues	57
Details	BROMODOMAIN_1 Bromodomain signature. FkdFiklpSrkfhp..QYYykIqqpMsineIksrdye....YedgpsnflldvelLtkNCqaY

Chain	Residue	Details
A	PHE77-TYR133
A	SER210-PHE267

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	315
Details	Domain: {"description":"Bromo 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	333
Details	Domain: {"description":"Bromo 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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