2QZV
Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0008283 | biological_process | cell population proliferation |
| A | 0019901 | molecular_function | protein kinase binding |
| A | 0019903 | molecular_function | protein phosphatase binding |
| A | 0038127 | biological_process | ERBB signaling pathway |
| A | 0042059 | biological_process | negative regulation of epidermal growth factor receptor signaling pathway |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0072376 | biological_process | protein activation cascade |
| A | 1990904 | cellular_component | ribonucleoprotein complex |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0008283 | biological_process | cell population proliferation |
| B | 0019901 | molecular_function | protein kinase binding |
| B | 0019903 | molecular_function | protein phosphatase binding |
| B | 0038127 | biological_process | ERBB signaling pathway |
| B | 0042059 | biological_process | negative regulation of epidermal growth factor receptor signaling pathway |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0048471 | cellular_component | perinuclear region of cytoplasm |
| B | 0072376 | biological_process | protein activation cascade |
| B | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKNGDKVMAgdEW |
| Chain | Residue | Details |
| A | ASP131-TRP143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 108 |
| Details | Repeat: {"description":"MVP 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 104 |
| Details | Repeat: {"description":"MVP 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 108 |
| Details | Repeat: {"description":"MVP 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 110 |
| Details | Repeat: {"description":"MVP 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 154 |
| Details | Repeat: {"description":"MVP 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 124 |
| Details | Repeat: {"description":"MVP 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00571","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19150846","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 38 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"UniProtKB","id":"Q14764","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"22673903","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"UniProtKB","id":"Q14764","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
