Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001533 | cellular_component | cornified envelope |
A | 0002803 | biological_process | positive regulation of antibacterial peptide production |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0008233 | molecular_function | peptidase activity |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0008544 | biological_process | epidermis development |
A | 0022617 | biological_process | extracellular matrix disassembly |
A | 0030141 | cellular_component | secretory granule |
A | 0097209 | cellular_component | epidermal lamellar body |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE K7J A 300 |
Chain | Residue |
A | HIS57 |
A | THR217 |
A | PHE218 |
A | CYS220 |
A | GLN221 |
A | HOH627 |
A | HOH653 |
A | HOH692 |
A | HOH700 |
A | HOH722 |
A | ALA190 |
A | CYS191 |
A | ASN192 |
A | GLY193 |
A | SER195 |
A | SER214 |
A | TRP215 |
A | GLY216 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. NAcnGDSGGPLV |
Chain | Residue | Details |
A | ASN189-VAL200 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Major binding site for inhibitory zinc or copper |
Chain | Residue | Details |
A | HIS99 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN239 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 | |
site_id | CSA2 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 | |
A | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | HIS57 | |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY193 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY196 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |