2QT1

Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006741	biological_process	NADP+ biosynthetic process
A	0009435	biological_process	NAD+ biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0019674	biological_process	NAD+ metabolic process
A	0034355	biological_process	NAD+ biosynthetic process via the salvage pathway
A	0046495	biological_process	nicotinamide riboside metabolic process
A	0046872	molecular_function	metal ion binding
A	0050262	molecular_function	ribosylnicotinamide kinase activity
A	0061769	molecular_function	ribosylnicotinate kinase activity
A	1901847	biological_process	nicotinate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PO4 A 201

Chain	Residue
A	ASN13
A	UNX206
A	HOH327
A	HOH346
A	SER14
A	GLY15
A	LYS16
A	THR17
A	ARG132
A	UNX203
A	UNX204
A	UNX205

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NNR A 202

Chain	Residue
A	ASP36
A	PHE39
A	TYR55
A	ASP56
A	PHE100
A	ARG129
A	TYR134
A	GLN135
A	UNX203
A	UNX204
A	UNX205
A	UNX206
A	HOH376

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE UNX A 203

Chain	Residue
A	THR12
A	ARG132
A	TYR134
A	PO4201
A	NNR202
A	UNX204
A	UNX205
A	UNX206

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE UNX A 204

Chain	Residue
A	ASP36
A	PO4201
A	NNR202
A	UNX203
A	UNX205
A	UNX206

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE UNX A 205

Chain	Residue
A	THR12
A	LYS16
A	PO4201
A	NNR202
A	UNX203
A	UNX204
A	UNX206
A	HOH376

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE UNX A 206

Chain	Residue
A	ASP36
A	PO4201
A	NNR202
A	UNX203
A	UNX204
A	UNX205
A	HOH346

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE UNX A 207

Chain	Residue
A	HOH303
A	HOH313

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE UNX A 208

Chain	Residue
A	ARG114
A	SER115
A	VAL166

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE UNX A 209

Chain	Residue
A	MSE74
A	GLU75
A	ARG78
A	LYS172
A	ASP176
A	HOH365

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17698003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QG6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QSZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QSY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17698003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17698003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QG6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QSZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17698003","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17914902","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QT0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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