2QQL

Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001525	biological_process	angiogenesis
A	0005021	molecular_function	vascular endothelial growth factor receptor activity
A	0007411	biological_process	axon guidance
A	0017154	molecular_function	semaphorin receptor activity
A	0038084	biological_process	vascular endothelial growth factor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS01286
Number of Residues	17
Details	FA58C_2 Coagulation factors 5/8 type C domain (FA58C) signature 2. Pqtwhsgia..LRlELfGC

Chain	Residue	Details
A	PRO411-CYS427
A	PRO575-CYS592

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

---

site_id	PS01285
Number of Residues	30
Details	FA58C_1 Coagulation factors 5/8 type C domain (FA58C) signature 1. GWtpnldsnke......YLqVDlrfltmLtaIaTQG

Chain	Residue	Details
A	GLY317-GLY346
A	GLY473-GLY505

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:17989695, ECO:0007744|PDB:2QQO

Chain	Residue	Details
A	GLU197
A	ASP211
A	ASP252

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17989695, ECO:0007744|PDB:2QQK

Chain	Residue	Details
A	ASN152
A	ASN157

---