2QMH

structure of V267F mutant HprK/P

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000155	molecular_function	phosphorelay sensor kinase activity
A	0000160	biological_process	phosphorelay signal transduction system
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006109	biological_process	regulation of carbohydrate metabolic process
B	0000155	molecular_function	phosphorelay sensor kinase activity
B	0000160	biological_process	phosphorelay signal transduction system
B	0004672	molecular_function	protein kinase activity
B	0005524	molecular_function	ATP binding
B	0006109	biological_process	regulation of carbohydrate metabolic process
C	0000155	molecular_function	phosphorelay sensor kinase activity
C	0000160	biological_process	phosphorelay signal transduction system
C	0004672	molecular_function	protein kinase activity
C	0005524	molecular_function	ATP binding
C	0006109	biological_process	regulation of carbohydrate metabolic process
D	0000155	molecular_function	phosphorelay sensor kinase activity
D	0000160	biological_process	phosphorelay signal transduction system
D	0004672	molecular_function	protein kinase activity
D	0005524	molecular_function	ATP binding
D	0006109	biological_process	regulation of carbohydrate metabolic process
E	0000155	molecular_function	phosphorelay sensor kinase activity
E	0000160	biological_process	phosphorelay signal transduction system
E	0004672	molecular_function	protein kinase activity
E	0005524	molecular_function	ATP binding
E	0006109	biological_process	regulation of carbohydrate metabolic process
F	0000155	molecular_function	phosphorelay sensor kinase activity
F	0000160	biological_process	phosphorelay signal transduction system
F	0004672	molecular_function	protein kinase activity
F	0005524	molecular_function	ATP binding
F	0006109	biological_process	regulation of carbohydrate metabolic process
G	0000155	molecular_function	phosphorelay sensor kinase activity
G	0000160	biological_process	phosphorelay signal transduction system
G	0004672	molecular_function	protein kinase activity
G	0005524	molecular_function	ATP binding
G	0006109	biological_process	regulation of carbohydrate metabolic process
H	0000155	molecular_function	phosphorelay sensor kinase activity
H	0000160	biological_process	phosphorelay signal transduction system
H	0004672	molecular_function	protein kinase activity
H	0005524	molecular_function	ATP binding
H	0006109	biological_process	regulation of carbohydrate metabolic process
I	0000155	molecular_function	phosphorelay sensor kinase activity
I	0000160	biological_process	phosphorelay signal transduction system
I	0004672	molecular_function	protein kinase activity
I	0005524	molecular_function	ATP binding
I	0006109	biological_process	regulation of carbohydrate metabolic process
J	0000155	molecular_function	phosphorelay sensor kinase activity
J	0000160	biological_process	phosphorelay signal transduction system
J	0004672	molecular_function	protein kinase activity
J	0005524	molecular_function	ATP binding
J	0006109	biological_process	regulation of carbohydrate metabolic process
K	0000155	molecular_function	phosphorelay sensor kinase activity
K	0000160	biological_process	phosphorelay signal transduction system
K	0004672	molecular_function	protein kinase activity
K	0005524	molecular_function	ATP binding
K	0006109	biological_process	regulation of carbohydrate metabolic process
L	0000155	molecular_function	phosphorelay sensor kinase activity
L	0000160	biological_process	phosphorelay signal transduction system
L	0004672	molecular_function	protein kinase activity
L	0005524	molecular_function	ATP binding
L	0006109	biological_process	regulation of carbohydrate metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	ACT_SITE:

Chain	Residue	Details
E	HIS140
E	LYS161
E	ARG245
F	HIS140
F	LYS161
F	ARG245
G	HIS140
G	LYS161
G	ARG245
H	HIS140
H	LYS161
H	ARG245
I	HIS140
I	LYS161
I	ARG245
J	HIS140
J	LYS161
J	ARG245
K	HIS140
K	LYS161
K	ARG245
L	HIS140
L	LYS161
L	ARG245
A	HIS140
A	LYS161
A	ARG245
B	HIS140
B	LYS161
B	ARG245
C	HIS140
C	LYS161
C	ARG245
D	HIS140
D	LYS161
D	ARG245

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site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity

Chain	Residue	Details
A	ASP179
B	ASP179
C	ASP179
D	ASP179
E	ASP179
F	ASP179
G	ASP179
H	ASP179
I	ASP179
J	ASP179
K	ASP179
L	ASP179

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site_id	SWS_FT_FI3
Number of Residues	36
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
E	GLY155
E	SER162
E	GLU204
F	GLY155
F	SER162
F	GLU204
G	GLY155
G	SER162
G	GLU204
H	GLY155
H	SER162
H	GLU204
I	GLY155
I	SER162
I	GLU204
J	GLY155
J	SER162
J	GLU204
K	GLY155
K	SER162
K	GLU204
L	GLY155
L	SER162
L	GLU204
A	GLY155
A	SER162
A	GLU204
B	GLY155
B	SER162
B	GLU204
C	GLY155
C	SER162
C	GLU204
D	GLY155
D	SER162
D	GLU204

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