2QFI

Structure of the zinc transporter YiiP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005381	molecular_function	iron ion transmembrane transporter activity
A	0005385	molecular_function	zinc ion transmembrane transporter activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006812	biological_process	monoatomic cation transport
A	0006826	biological_process	iron ion transport
A	0006829	biological_process	zinc ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006882	biological_process	intracellular zinc ion homeostasis
A	0008324	molecular_function	monoatomic cation transmembrane transporter activity
A	0015086	molecular_function	cadmium ion transmembrane transporter activity
A	0015093	molecular_function	ferrous iron transmembrane transporter activity
A	0015297	molecular_function	antiporter activity
A	0015341	molecular_function	zinc efflux antiporter activity
A	0016020	cellular_component	membrane
A	0034755	biological_process	iron ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
A	0046873	molecular_function	metal ion transmembrane transporter activity
A	0055085	biological_process	transmembrane transport
A	0070574	biological_process	cadmium ion transmembrane transport
A	0071577	biological_process	zinc ion transmembrane transport
A	0140826	molecular_function	zinc:proton antiporter activity
B	0005381	molecular_function	iron ion transmembrane transporter activity
B	0005385	molecular_function	zinc ion transmembrane transporter activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006812	biological_process	monoatomic cation transport
B	0006826	biological_process	iron ion transport
B	0006829	biological_process	zinc ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0006882	biological_process	intracellular zinc ion homeostasis
B	0008324	molecular_function	monoatomic cation transmembrane transporter activity
B	0015086	molecular_function	cadmium ion transmembrane transporter activity
B	0015093	molecular_function	ferrous iron transmembrane transporter activity
B	0015297	molecular_function	antiporter activity
B	0015341	molecular_function	zinc efflux antiporter activity
B	0016020	cellular_component	membrane
B	0034755	biological_process	iron ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
B	0046873	molecular_function	metal ion transmembrane transporter activity
B	0055085	biological_process	transmembrane transport
B	0070574	biological_process	cadmium ion transmembrane transport
B	0071577	biological_process	zinc ion transmembrane transport
B	0140826	molecular_function	zinc:proton antiporter activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 301

Chain	Residue
B	HIS232
B	ILE245
B	ASP285
B	VAL289

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 302

Chain	Residue
A	HIS261
A	ASP265
A	HIS283
A	ASP285
A	ZN306

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 303

Chain	Residue
A	ALA67
A	ASP68
A	SER72
A	HIS75

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 304

Chain	Residue
B	HIS261
B	ASP265
B	HIS283
B	ASP285

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 305

Chain	Residue
B	ALA67
B	ASP68
B	SER72
B	HIS75

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 306

Chain	Residue
A	HIS232
A	ILE245
A	ASP285
A	ZN302

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 307

Chain	Residue
A	ASP45
A	ASP49
A	ASP157

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	194
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	84
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"16049012","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	64
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"16049012","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17717154","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16790427","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2QFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H90","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17717154","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H90","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3H90","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17717154","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19749753","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16049012","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2QFI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3H90","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---