2Q70
Estrogen receptor alpha ligand-binding domain complxed to a benzopyran ligand
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DC8 A 50 |
| Chain | Residue |
| A | HOH3 |
| A | GLU353 |
| A | LEU384 |
| A | LEU387 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | HIS524 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DC8 B 51 |
| Chain | Residue |
| B | GLU353 |
| B | LEU384 |
| B | LEU387 |
| B | ARG394 |
| B | PHE404 |
| B | ILE424 |
| B | HIS524 |
| B | LEU525 |
| B | HOH2 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| A | TYR537 | |
| B | TYR537 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 |
