2Q3H

The crystal structure of RhouA in the GDP-bound state.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0007264	biological_process	small GTPase-mediated signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1

Chain	Residue
A	THR63
A	GDP3444
A	HOH3499
A	HOH3500
A	HOH3501
A	HOH3504

---

site_id	AC2
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GDP A 3444

Chain	Residue
A	GLY61
A	LYS62
A	THR63
A	SER64
A	GLN162
A	ASP164
A	LEU165
A	SER204
A	ALA205
A	LEU206
A	HOH3450
A	HOH3454
A	HOH3465
A	HOH3466
A	HOH3482
A	HOH3499
A	HOH3500
A	HOH3501
A	HOH3533
A	MG1
A	ALA59
A	VAL60

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11459829","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26598620","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLN107

---