2Q3E
Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001702 | biological_process | gastrulation with mouth forming second |
| A | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| A | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| A | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| A | 0034214 | biological_process | protein hexamerization |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0048666 | biological_process | neuron development |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0001702 | biological_process | gastrulation with mouth forming second |
| B | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| B | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| B | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| B | 0034214 | biological_process | protein hexamerization |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0048666 | biological_process | neuron development |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070062 | cellular_component | extracellular exosome |
| C | 0001702 | biological_process | gastrulation with mouth forming second |
| C | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| C | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| C | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| C | 0034214 | biological_process | protein hexamerization |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0048666 | biological_process | neuron development |
| C | 0051287 | molecular_function | NAD binding |
| C | 0070062 | cellular_component | extracellular exosome |
| D | 0001702 | biological_process | gastrulation with mouth forming second |
| D | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| D | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| D | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| D | 0034214 | biological_process | protein hexamerization |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0048666 | biological_process | neuron development |
| D | 0051287 | molecular_function | NAD binding |
| D | 0070062 | cellular_component | extracellular exosome |
| E | 0001702 | biological_process | gastrulation with mouth forming second |
| E | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| E | 0005634 | cellular_component | nucleus |
| E | 0005654 | cellular_component | nucleoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| E | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| E | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| E | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| E | 0034214 | biological_process | protein hexamerization |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0048666 | biological_process | neuron development |
| E | 0051287 | molecular_function | NAD binding |
| E | 0070062 | cellular_component | extracellular exosome |
| F | 0001702 | biological_process | gastrulation with mouth forming second |
| F | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| F | 0005634 | cellular_component | nucleus |
| F | 0005654 | cellular_component | nucleoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| F | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| F | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| F | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| F | 0034214 | biological_process | protein hexamerization |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0048666 | biological_process | neuron development |
| F | 0051287 | molecular_function | NAD binding |
| F | 0070062 | cellular_component | extracellular exosome |
| G | 0001702 | biological_process | gastrulation with mouth forming second |
| G | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| G | 0005634 | cellular_component | nucleus |
| G | 0005654 | cellular_component | nucleoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| G | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| G | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| G | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| G | 0034214 | biological_process | protein hexamerization |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0048666 | biological_process | neuron development |
| G | 0051287 | molecular_function | NAD binding |
| G | 0070062 | cellular_component | extracellular exosome |
| H | 0001702 | biological_process | gastrulation with mouth forming second |
| H | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| H | 0005634 | cellular_component | nucleus |
| H | 0005654 | cellular_component | nucleoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| H | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| H | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| H | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| H | 0034214 | biological_process | protein hexamerization |
| H | 0042802 | molecular_function | identical protein binding |
| H | 0048666 | biological_process | neuron development |
| H | 0051287 | molecular_function | NAD binding |
| H | 0070062 | cellular_component | extracellular exosome |
| I | 0001702 | biological_process | gastrulation with mouth forming second |
| I | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| I | 0005634 | cellular_component | nucleus |
| I | 0005654 | cellular_component | nucleoplasm |
| I | 0005829 | cellular_component | cytosol |
| I | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| I | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| I | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| I | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| I | 0034214 | biological_process | protein hexamerization |
| I | 0042802 | molecular_function | identical protein binding |
| I | 0048666 | biological_process | neuron development |
| I | 0051287 | molecular_function | NAD binding |
| I | 0070062 | cellular_component | extracellular exosome |
| J | 0001702 | biological_process | gastrulation with mouth forming second |
| J | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| J | 0005634 | cellular_component | nucleus |
| J | 0005654 | cellular_component | nucleoplasm |
| J | 0005829 | cellular_component | cytosol |
| J | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| J | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| J | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| J | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| J | 0034214 | biological_process | protein hexamerization |
| J | 0042802 | molecular_function | identical protein binding |
| J | 0048666 | biological_process | neuron development |
| J | 0051287 | molecular_function | NAD binding |
| J | 0070062 | cellular_component | extracellular exosome |
| K | 0001702 | biological_process | gastrulation with mouth forming second |
| K | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| K | 0005634 | cellular_component | nucleus |
| K | 0005654 | cellular_component | nucleoplasm |
| K | 0005829 | cellular_component | cytosol |
| K | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| K | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| K | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| K | 0016491 | molecular_function | oxidoreductase activity |
| K | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| K | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| K | 0034214 | biological_process | protein hexamerization |
| K | 0042802 | molecular_function | identical protein binding |
| K | 0048666 | biological_process | neuron development |
| K | 0051287 | molecular_function | NAD binding |
| K | 0070062 | cellular_component | extracellular exosome |
| L | 0001702 | biological_process | gastrulation with mouth forming second |
| L | 0003979 | molecular_function | UDP-glucose 6-dehydrogenase activity |
| L | 0005634 | cellular_component | nucleus |
| L | 0005654 | cellular_component | nucleoplasm |
| L | 0005829 | cellular_component | cytosol |
| L | 0006024 | biological_process | glycosaminoglycan biosynthetic process |
| L | 0006065 | biological_process | UDP-glucuronate biosynthetic process |
| L | 0015012 | biological_process | heparan sulfate proteoglycan biosynthetic process |
| L | 0016491 | molecular_function | oxidoreductase activity |
| L | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| L | 0030206 | biological_process | chondroitin sulfate biosynthetic process |
| L | 0034214 | biological_process | protein hexamerization |
| L | 0042802 | molecular_function | identical protein binding |
| L | 0048666 | biological_process | neuron development |
| L | 0051287 | molecular_function | NAD binding |
| L | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 3001 |
| Chain | Residue |
| A | MET419 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL G 3002 |
| Chain | Residue |
| G | MET419 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL I 3003 |
| Chain | Residue |
| I | MET419 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL F 3004 |
| Chain | Residue |
| F | MET419 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 3005 |
| Chain | Residue |
| C | MET419 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL D 3006 |
| Chain | Residue |
| D | MET419 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL L 3007 |
| Chain | Residue |
| L | MET419 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL K 3008 |
| Chain | Residue |
| K | MET419 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 3009 |
| Chain | Residue |
| B | MET419 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL H 3010 |
| Chain | Residue |
| H | MET419 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL E 3011 |
| Chain | Residue |
| E | MET419 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL J 3012 |
| Chain | Residue |
| J | MET419 |
| site_id | BC4 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAI A 500 |
| Chain | Residue |
| A | ILE10 |
| A | GLY11 |
| A | GLY13 |
| A | TYR14 |
| A | VAL15 |
| A | ASP36 |
| A | VAL37 |
| A | ARG41 |
| A | SER88 |
| A | VAL89 |
| A | ASN90 |
| A | THR91 |
| A | TYR108 |
| A | SER130 |
| A | THR131 |
| A | GLU161 |
| A | LEU163 |
| A | GLU165 |
| A | CYS276 |
| A | LYS279 |
| A | ARG346 |
| A | UPG501 |
| A | HOH3010 |
| A | HOH3020 |
| A | HOH3024 |
| A | HOH3033 |
| A | HOH3042 |
| A | HOH3045 |
| A | HOH3130 |
| A | HOH3136 |
| A | HOH3161 |
| site_id | BC5 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG A 501 |
| Chain | Residue |
| A | GLU161 |
| A | PHE162 |
| A | LEU163 |
| A | ALA164 |
| A | GLU165 |
| A | LYS220 |
| A | ASN224 |
| A | ILE231 |
| A | PHE265 |
| A | LEU266 |
| A | LYS267 |
| A | SER269 |
| A | PHE272 |
| A | GLY273 |
| A | CYS276 |
| A | PHE277 |
| A | PHE338 |
| A | LYS339 |
| A | ARG442 |
| A | NAI500 |
| A | HOH3020 |
| A | HOH3021 |
| A | HOH3041 |
| A | HOH3042 |
| A | HOH3044 |
| A | HOH3052 |
| A | HOH3072 |
| A | HOH3085 |
| A | HOH3127 |
| B | ARG260 |
| site_id | BC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI B 500 |
| Chain | Residue |
| B | HOH3059 |
| B | HOH3144 |
| B | HOH3155 |
| B | HOH3156 |
| B | ILE10 |
| B | GLY11 |
| B | GLY13 |
| B | TYR14 |
| B | VAL15 |
| B | ASP36 |
| B | VAL37 |
| B | ARG41 |
| B | SER88 |
| B | VAL89 |
| B | ASN90 |
| B | THR91 |
| B | TYR108 |
| B | SER130 |
| B | THR131 |
| B | GLU161 |
| B | LEU163 |
| B | GLU165 |
| B | CYS276 |
| B | LYS279 |
| B | ARG346 |
| B | UPG501 |
| B | HOH3013 |
| B | HOH3021 |
| B | HOH3024 |
| B | HOH3040 |
| site_id | BC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG B 501 |
| Chain | Residue |
| A | ARG260 |
| B | GLU161 |
| B | PHE162 |
| B | LEU163 |
| B | ALA164 |
| B | GLU165 |
| B | LYS220 |
| B | ASN224 |
| B | ILE231 |
| B | PHE265 |
| B | LEU266 |
| B | LYS267 |
| B | SER269 |
| B | PHE272 |
| B | GLY273 |
| B | CYS276 |
| B | PHE277 |
| B | PHE338 |
| B | LYS339 |
| B | ARG442 |
| B | NAI500 |
| B | HOH3013 |
| B | HOH3019 |
| B | HOH3023 |
| B | HOH3024 |
| B | HOH3027 |
| B | HOH3036 |
| B | HOH3056 |
| B | HOH3077 |
| site_id | BC8 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAI C 500 |
| Chain | Residue |
| C | ILE10 |
| C | GLY11 |
| C | GLY13 |
| C | TYR14 |
| C | VAL15 |
| C | ASP36 |
| C | VAL37 |
| C | ARG41 |
| C | SER88 |
| C | VAL89 |
| C | ASN90 |
| C | THR91 |
| C | TYR108 |
| C | SER130 |
| C | THR131 |
| C | GLU161 |
| C | LEU163 |
| C | GLU165 |
| C | CYS276 |
| C | LYS279 |
| C | ARG346 |
| C | UPG501 |
| C | HOH3015 |
| C | HOH3019 |
| C | HOH3020 |
| C | HOH3021 |
| C | HOH3024 |
| C | HOH3066 |
| C | HOH3115 |
| C | HOH3130 |
| C | HOH3269 |
| site_id | BC9 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG C 501 |
| Chain | Residue |
| C | GLU161 |
| C | PHE162 |
| C | LEU163 |
| C | ALA164 |
| C | GLU165 |
| C | LYS220 |
| C | ASN224 |
| C | ILE231 |
| C | PHE265 |
| C | LEU266 |
| C | LYS267 |
| C | SER269 |
| C | PHE272 |
| C | GLY273 |
| C | CYS276 |
| C | PHE277 |
| C | PHE338 |
| C | LYS339 |
| C | ARG442 |
| C | NAI500 |
| C | HOH3015 |
| C | HOH3018 |
| C | HOH3019 |
| C | HOH3028 |
| C | HOH3035 |
| C | HOH3050 |
| C | HOH3053 |
| C | HOH3076 |
| C | HOH3145 |
| D | ARG260 |
| site_id | CC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI D 500 |
| Chain | Residue |
| D | ILE10 |
| D | GLY11 |
| D | GLY13 |
| D | TYR14 |
| D | VAL15 |
| D | ASP36 |
| D | VAL37 |
| D | ARG41 |
| D | SER88 |
| D | VAL89 |
| D | ASN90 |
| D | THR91 |
| D | TYR108 |
| D | SER130 |
| D | THR131 |
| D | GLU161 |
| D | LEU163 |
| D | GLU165 |
| D | CYS276 |
| D | LYS279 |
| D | ARG346 |
| D | UPG501 |
| D | HOH3013 |
| D | HOH3018 |
| D | HOH3028 |
| D | HOH3044 |
| D | HOH3103 |
| D | HOH3159 |
| D | HOH3181 |
| D | HOH3182 |
| site_id | CC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG D 501 |
| Chain | Residue |
| C | ARG260 |
| D | GLU161 |
| D | PHE162 |
| D | LEU163 |
| D | ALA164 |
| D | GLU165 |
| D | LYS220 |
| D | ASN224 |
| D | ILE231 |
| D | PHE265 |
| D | LEU266 |
| D | LYS267 |
| D | SER269 |
| D | PHE272 |
| D | GLY273 |
| D | CYS276 |
| D | PHE277 |
| D | PHE338 |
| D | LYS339 |
| D | ARG442 |
| D | NAI500 |
| D | HOH3013 |
| D | HOH3019 |
| D | HOH3021 |
| D | HOH3026 |
| D | HOH3037 |
| D | HOH3038 |
| D | HOH3044 |
| D | HOH3052 |
| D | HOH3164 |
| site_id | CC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAI E 500 |
| Chain | Residue |
| E | ILE10 |
| E | GLY11 |
| E | GLY13 |
| E | TYR14 |
| E | VAL15 |
| E | ASP36 |
| E | VAL37 |
| E | ARG41 |
| E | SER88 |
| E | VAL89 |
| E | ASN90 |
| E | THR91 |
| E | TYR108 |
| E | SER130 |
| E | THR131 |
| E | GLU161 |
| E | LEU163 |
| E | GLU165 |
| E | CYS276 |
| E | LYS279 |
| E | ARG346 |
| E | UPG501 |
| E | HOH3025 |
| E | HOH3026 |
| E | HOH3035 |
| E | HOH3050 |
| E | HOH3051 |
| E | HOH3067 |
| E | HOH3193 |
| site_id | CC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG E 501 |
| Chain | Residue |
| E | GLU161 |
| E | PHE162 |
| E | LEU163 |
| E | ALA164 |
| E | GLU165 |
| E | LYS220 |
| E | ASN224 |
| E | ILE231 |
| E | PHE265 |
| E | LEU266 |
| E | LYS267 |
| E | SER269 |
| E | PHE272 |
| E | GLY273 |
| E | CYS276 |
| E | PHE277 |
| E | PHE338 |
| E | LYS339 |
| E | ARG442 |
| E | NAI500 |
| E | HOH3017 |
| E | HOH3025 |
| E | HOH3027 |
| E | HOH3030 |
| E | HOH3037 |
| E | HOH3050 |
| E | HOH3086 |
| E | HOH3116 |
| E | HOH3129 |
| F | ARG260 |
| site_id | CC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAI F 500 |
| Chain | Residue |
| F | ILE10 |
| F | GLY11 |
| F | GLY13 |
| F | TYR14 |
| F | VAL15 |
| F | ASP36 |
| F | VAL37 |
| F | ARG41 |
| F | SER88 |
| F | VAL89 |
| F | ASN90 |
| F | THR91 |
| F | TYR108 |
| F | SER130 |
| F | THR131 |
| F | GLU161 |
| F | LEU163 |
| F | GLU165 |
| F | CYS276 |
| F | LYS279 |
| F | ARG346 |
| F | UPG501 |
| F | HOH3011 |
| F | HOH3019 |
| F | HOH3026 |
| F | HOH3036 |
| F | HOH3088 |
| F | HOH3163 |
| F | HOH3164 |
| site_id | CC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG F 501 |
| Chain | Residue |
| E | ARG260 |
| F | GLU161 |
| F | PHE162 |
| F | LEU163 |
| F | ALA164 |
| F | GLU165 |
| F | LYS220 |
| F | ASN224 |
| F | ILE231 |
| F | PHE265 |
| F | LEU266 |
| F | LYS267 |
| F | SER269 |
| F | PHE272 |
| F | GLY273 |
| F | CYS276 |
| F | PHE277 |
| F | PHE338 |
| F | LYS339 |
| F | ARG442 |
| F | NAI500 |
| F | HOH3011 |
| F | HOH3017 |
| F | HOH3023 |
| F | HOH3026 |
| F | HOH3029 |
| F | HOH3041 |
| F | HOH3042 |
| F | HOH3053 |
| F | HOH3150 |
| site_id | CC7 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAI G 500 |
| Chain | Residue |
| G | ILE10 |
| G | GLY11 |
| G | GLY13 |
| G | TYR14 |
| G | VAL15 |
| G | ASP36 |
| G | VAL37 |
| G | ARG41 |
| G | SER88 |
| G | VAL89 |
| G | ASN90 |
| G | THR91 |
| G | TYR108 |
| G | SER130 |
| G | THR131 |
| G | GLU161 |
| G | LEU163 |
| G | GLU165 |
| G | CYS276 |
| G | LYS279 |
| G | ARG346 |
| G | UPG501 |
| G | HOH3007 |
| G | HOH3008 |
| G | HOH3022 |
| G | HOH3033 |
| G | HOH3059 |
| G | HOH3079 |
| G | HOH3088 |
| G | HOH3123 |
| G | HOH3130 |
| site_id | CC8 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG G 501 |
| Chain | Residue |
| G | GLU161 |
| G | PHE162 |
| G | LEU163 |
| G | ALA164 |
| G | GLU165 |
| G | LYS220 |
| G | ASN224 |
| G | ILE231 |
| G | PHE265 |
| G | LEU266 |
| G | LYS267 |
| G | SER269 |
| G | PHE272 |
| G | GLY273 |
| G | CYS276 |
| G | PHE277 |
| G | PHE338 |
| G | LYS339 |
| G | ARG442 |
| G | NAI500 |
| G | HOH3007 |
| G | HOH3022 |
| G | HOH3040 |
| G | HOH3041 |
| G | HOH3063 |
| G | HOH3068 |
| G | HOH3074 |
| G | HOH3077 |
| H | ARG260 |
| site_id | CC9 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI H 500 |
| Chain | Residue |
| H | ILE10 |
| H | GLY11 |
| H | GLY13 |
| H | TYR14 |
| H | VAL15 |
| H | ASP36 |
| H | VAL37 |
| H | ARG41 |
| H | SER88 |
| H | VAL89 |
| H | ASN90 |
| H | THR91 |
| H | TYR108 |
| H | SER130 |
| H | THR131 |
| H | GLU161 |
| H | LEU163 |
| H | GLU165 |
| H | CYS276 |
| H | LYS279 |
| H | ARG346 |
| H | UPG501 |
| H | HOH3014 |
| H | HOH3021 |
| H | HOH3041 |
| H | HOH3048 |
| H | HOH3095 |
| H | HOH3097 |
| H | HOH3098 |
| H | HOH3109 |
| site_id | DC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG H 501 |
| Chain | Residue |
| G | ARG260 |
| H | GLU161 |
| H | PHE162 |
| H | LEU163 |
| H | ALA164 |
| H | GLU165 |
| H | LYS220 |
| H | ASN224 |
| H | ILE231 |
| H | PHE265 |
| H | LEU266 |
| H | LYS267 |
| H | SER269 |
| H | PHE272 |
| H | GLY273 |
| H | CYS276 |
| H | PHE277 |
| H | PHE338 |
| H | LYS339 |
| H | ARG442 |
| H | NAI500 |
| H | HOH3014 |
| H | HOH3017 |
| H | HOH3024 |
| H | HOH3034 |
| H | HOH3048 |
| H | HOH3053 |
| H | HOH3054 |
| H | HOH3068 |
| site_id | DC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAI I 500 |
| Chain | Residue |
| I | ILE10 |
| I | GLY11 |
| I | GLY13 |
| I | TYR14 |
| I | VAL15 |
| I | ASP36 |
| I | VAL37 |
| I | ARG41 |
| I | SER88 |
| I | VAL89 |
| I | ASN90 |
| I | THR91 |
| I | TYR108 |
| I | SER130 |
| I | THR131 |
| I | GLU161 |
| I | LEU163 |
| I | GLU165 |
| I | CYS276 |
| I | LYS279 |
| I | ARG346 |
| I | UPG501 |
| I | HOH3010 |
| I | HOH3029 |
| I | HOH3036 |
| I | HOH3039 |
| I | HOH3042 |
| I | HOH3182 |
| I | HOH3183 |
| site_id | DC3 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG I 501 |
| Chain | Residue |
| I | GLU161 |
| I | PHE162 |
| I | LEU163 |
| I | ALA164 |
| I | GLU165 |
| I | LYS220 |
| I | ASN224 |
| I | ILE231 |
| I | PHE265 |
| I | LEU266 |
| I | LYS267 |
| I | SER269 |
| I | PHE272 |
| I | GLY273 |
| I | CYS276 |
| I | PHE277 |
| I | PHE338 |
| I | LYS339 |
| I | ARG442 |
| I | NAI500 |
| I | HOH3019 |
| I | HOH3026 |
| I | HOH3029 |
| I | HOH3036 |
| I | HOH3056 |
| I | HOH3078 |
| I | HOH3109 |
| I | HOH3120 |
| I | HOH3172 |
| J | ARG260 |
| site_id | DC4 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAI J 500 |
| Chain | Residue |
| J | ILE10 |
| J | GLY11 |
| J | GLY13 |
| J | TYR14 |
| J | VAL15 |
| J | ASP36 |
| J | VAL37 |
| J | ARG41 |
| J | SER88 |
| J | VAL89 |
| J | ASN90 |
| J | THR91 |
| J | TYR108 |
| J | ALA111 |
| J | SER130 |
| J | THR131 |
| J | GLU161 |
| J | LEU163 |
| J | GLU165 |
| J | CYS276 |
| J | LYS279 |
| J | ARG346 |
| J | UPG501 |
| J | HOH3021 |
| J | HOH3027 |
| J | HOH3046 |
| J | HOH3049 |
| J | HOH3051 |
| J | HOH3063 |
| J | HOH3173 |
| J | HOH3174 |
| site_id | DC5 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE UPG J 501 |
| Chain | Residue |
| I | ARG260 |
| J | GLU161 |
| J | PHE162 |
| J | LEU163 |
| J | ALA164 |
| J | GLU165 |
| J | LYS220 |
| J | ASN224 |
| J | ILE231 |
| J | PHE265 |
| J | LEU266 |
| J | LYS267 |
| J | SER269 |
| J | PHE272 |
| J | GLY273 |
| J | CYS276 |
| J | PHE277 |
| J | PHE338 |
| J | LYS339 |
| J | ARG442 |
| J | NAI500 |
| J | HOH3021 |
| J | HOH3022 |
| J | HOH3029 |
| J | HOH3045 |
| J | HOH3046 |
| J | HOH3050 |
| J | HOH3062 |
| J | HOH3085 |
| J | HOH3164 |
| site_id | DC6 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAI K 500 |
| Chain | Residue |
| K | ILE10 |
| K | GLY11 |
| K | GLY13 |
| K | TYR14 |
| K | VAL15 |
| K | ASP36 |
| K | VAL37 |
| K | ARG41 |
| K | SER88 |
| K | VAL89 |
| K | ASN90 |
| K | THR91 |
| K | TYR108 |
| K | SER130 |
| K | THR131 |
| K | GLU161 |
| K | LEU163 |
| K | GLU165 |
| K | CYS276 |
| K | LYS279 |
| K | ARG346 |
| K | UPG501 |
| K | HOH3029 |
| K | HOH3031 |
| K | HOH3039 |
| K | HOH3042 |
| K | HOH3048 |
| K | HOH3125 |
| K | HOH3126 |
| K | HOH3162 |
| site_id | DC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG K 501 |
| Chain | Residue |
| K | GLU161 |
| K | PHE162 |
| K | LEU163 |
| K | ALA164 |
| K | GLU165 |
| K | LYS220 |
| K | ASN224 |
| K | ILE231 |
| K | PHE265 |
| K | LYS267 |
| K | SER269 |
| K | PHE272 |
| K | GLY273 |
| K | CYS276 |
| K | PHE277 |
| K | PHE338 |
| K | LYS339 |
| K | ARG442 |
| K | NAI500 |
| K | HOH3034 |
| K | HOH3042 |
| K | HOH3048 |
| K | HOH3050 |
| K | HOH3055 |
| K | HOH3057 |
| K | HOH3062 |
| K | HOH3083 |
| K | HOH3201 |
| L | ARG260 |
| site_id | DC8 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAI L 500 |
| Chain | Residue |
| L | ILE10 |
| L | GLY11 |
| L | GLY13 |
| L | TYR14 |
| L | VAL15 |
| L | ASP36 |
| L | VAL37 |
| L | ARG41 |
| L | SER88 |
| L | VAL89 |
| L | ASN90 |
| L | THR91 |
| L | TYR108 |
| L | ALA111 |
| L | SER130 |
| L | THR131 |
| L | GLU161 |
| L | LEU163 |
| L | GLU165 |
| L | CYS276 |
| L | LYS279 |
| L | ARG346 |
| L | UPG501 |
| L | HOH3015 |
| L | HOH3017 |
| L | HOH3032 |
| L | HOH3048 |
| L | HOH3105 |
| L | HOH3144 |
| site_id | DC9 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE UPG L 501 |
| Chain | Residue |
| K | ARG260 |
| L | GLU161 |
| L | PHE162 |
| L | LEU163 |
| L | ALA164 |
| L | GLU165 |
| L | LYS220 |
| L | ASN224 |
| L | ILE231 |
| L | PHE265 |
| L | LYS267 |
| L | SER269 |
| L | PHE272 |
| L | GLY273 |
| L | CYS276 |
| L | PHE277 |
| L | PHE338 |
| L | LYS339 |
| L | ARG442 |
| L | NAI500 |
| L | HOH3015 |
| L | HOH3025 |
| L | HOH3029 |
| L | HOH3032 |
| L | HOH3036 |
| L | HOH3041 |
| L | HOH3070 |
| L | HOH3108 |
| L | HOH3111 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:22123821 |
| Chain | Residue | Details |
| A | GLU161 | |
| E | LYS220 | |
| F | GLU161 | |
| F | LYS220 | |
| G | GLU161 | |
| G | LYS220 | |
| H | GLU161 | |
| H | LYS220 | |
| I | GLU161 | |
| I | LYS220 | |
| J | GLU161 | |
| A | LYS220 | |
| J | LYS220 | |
| K | GLU161 | |
| K | LYS220 | |
| L | GLU161 | |
| L | LYS220 | |
| B | GLU161 | |
| B | LYS220 | |
| C | GLU161 | |
| C | LYS220 | |
| D | GLU161 | |
| D | LYS220 | |
| E | GLU161 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:21502315, ECO:0000269|PubMed:21984906, ECO:0000269|PubMed:22123821 |
| Chain | Residue | Details |
| A | CYS276 | |
| J | CYS276 | |
| K | CYS276 | |
| L | CYS276 | |
| B | CYS276 | |
| C | CYS276 | |
| D | CYS276 | |
| E | CYS276 | |
| F | CYS276 | |
| G | CYS276 | |
| H | CYS276 | |
| I | CYS276 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 60 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21502315, ECO:0000269|PubMed:21595445, ECO:0000269|PubMed:21984906, ECO:0007744|PDB:2Q3E, ECO:0007744|PDB:2QG4, ECO:0007744|PDB:3PRJ, ECO:0007744|PDB:3PTZ, ECO:0007744|PDB:3TDK |
| Chain | Residue | Details |
| A | GLY11 | |
| B | CYS276 | |
| C | GLY11 | |
| C | ASP36 | |
| C | ARG41 | |
| C | VAL89 | |
| C | CYS276 | |
| D | GLY11 | |
| D | ASP36 | |
| D | ARG41 | |
| D | VAL89 | |
| A | ASP36 | |
| D | CYS276 | |
| E | GLY11 | |
| E | ASP36 | |
| E | ARG41 | |
| E | VAL89 | |
| E | CYS276 | |
| F | GLY11 | |
| F | ASP36 | |
| F | ARG41 | |
| F | VAL89 | |
| A | ARG41 | |
| F | CYS276 | |
| G | GLY11 | |
| G | ASP36 | |
| G | ARG41 | |
| G | VAL89 | |
| G | CYS276 | |
| H | GLY11 | |
| H | ASP36 | |
| H | ARG41 | |
| H | VAL89 | |
| A | VAL89 | |
| H | CYS276 | |
| I | GLY11 | |
| I | ASP36 | |
| I | ARG41 | |
| I | VAL89 | |
| I | CYS276 | |
| J | GLY11 | |
| J | ASP36 | |
| J | ARG41 | |
| J | VAL89 | |
| A | CYS276 | |
| J | CYS276 | |
| K | GLY11 | |
| K | ASP36 | |
| K | ARG41 | |
| K | VAL89 | |
| K | CYS276 | |
| L | GLY11 | |
| L | ASP36 | |
| L | ARG41 | |
| L | VAL89 | |
| B | GLY11 | |
| L | CYS276 | |
| B | ASP36 | |
| B | ARG41 | |
| B | VAL89 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21502315, ECO:0000269|PubMed:21595445 |
| Chain | Residue | Details |
| A | SER130 | |
| J | SER130 | |
| K | SER130 | |
| L | SER130 | |
| B | SER130 | |
| C | SER130 | |
| D | SER130 | |
| E | SER130 | |
| F | SER130 | |
| G | SER130 | |
| H | SER130 | |
| I | SER130 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23106432, ECO:0000305|PubMed:21502315, ECO:0000305|PubMed:21595445, ECO:0007744|PDB:2QG4, ECO:0007744|PDB:3PRJ, ECO:0007744|PDB:3PTZ, ECO:0007744|PDB:4EDF |
| Chain | Residue | Details |
| A | GLU161 | |
| C | LYS220 | |
| C | LYS267 | |
| C | PHE338 | |
| D | GLU161 | |
| D | LYS220 | |
| D | LYS267 | |
| D | PHE338 | |
| E | GLU161 | |
| E | LYS220 | |
| E | LYS267 | |
| A | LYS220 | |
| E | PHE338 | |
| F | GLU161 | |
| F | LYS220 | |
| F | LYS267 | |
| F | PHE338 | |
| G | GLU161 | |
| G | LYS220 | |
| G | LYS267 | |
| G | PHE338 | |
| H | GLU161 | |
| A | LYS267 | |
| H | LYS220 | |
| H | LYS267 | |
| H | PHE338 | |
| I | GLU161 | |
| I | LYS220 | |
| I | LYS267 | |
| I | PHE338 | |
| J | GLU161 | |
| J | LYS220 | |
| J | LYS267 | |
| A | PHE338 | |
| J | PHE338 | |
| K | GLU161 | |
| K | LYS220 | |
| K | LYS267 | |
| K | PHE338 | |
| L | GLU161 | |
| L | LYS220 | |
| L | LYS267 | |
| L | PHE338 | |
| B | GLU161 | |
| B | LYS220 | |
| B | LYS267 | |
| B | PHE338 | |
| C | GLU161 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21502315, ECO:0007744|PDB:2Q3E, ECO:0007744|PDB:2QG4 |
| Chain | Residue | Details |
| A | GLU165 | |
| J | GLU165 | |
| K | GLU165 | |
| L | GLU165 | |
| B | GLU165 | |
| C | GLU165 | |
| D | GLU165 | |
| E | GLU165 | |
| F | GLU165 | |
| G | GLU165 | |
| H | GLU165 | |
| I | GLU165 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23106432, ECO:0000269|PubMed:27966912, ECO:0000305|PubMed:21502315, ECO:0000305|PubMed:21595445, ECO:0007744|PDB:2QG4, ECO:0007744|PDB:3PRJ, ECO:0007744|PDB:3PTZ, ECO:0007744|PDB:4EDF, ECO:0007744|PDB:5TJH |
| Chain | Residue | Details |
| A | ARG260 | |
| J | ARG260 | |
| K | ARG260 | |
| L | ARG260 | |
| B | ARG260 | |
| C | ARG260 | |
| D | ARG260 | |
| E | ARG260 | |
| F | ARG260 | |
| G | ARG260 | |
| H | ARG260 | |
| I | ARG260 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21502315, ECO:0000269|PubMed:21595445, ECO:0000269|PubMed:21984906, ECO:0000269|PubMed:22123821, ECO:0007744|PDB:2Q3E, ECO:0007744|PDB:2QG4, ECO:0007744|PDB:3PRJ, ECO:0007744|PDB:3PTZ, ECO:0007744|PDB:3TDK |
| Chain | Residue | Details |
| A | ARG346 | |
| J | ARG346 | |
| K | ARG346 | |
| L | ARG346 | |
| B | ARG346 | |
| C | ARG346 | |
| D | ARG346 | |
| E | ARG346 | |
| F | ARG346 | |
| G | ARG346 | |
| H | ARG346 | |
| I | ARG346 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22123821, ECO:0000269|PubMed:23106432, ECO:0000305|PubMed:21502315, ECO:0000305|PubMed:21595445, ECO:0007744|PDB:2QG4, ECO:0007744|PDB:3KHU, ECO:0007744|PDB:3PRJ, ECO:0007744|PDB:3PTZ, ECO:0007744|PDB:4EDF |
| Chain | Residue | Details |
| A | ARG442 | |
| J | ARG442 | |
| K | ARG442 | |
| L | ARG442 | |
| B | ARG442 | |
| C | ARG442 | |
| D | ARG442 | |
| E | ARG442 | |
| F | ARG442 | |
| G | ARG442 | |
| H | ARG442 | |
| I | ARG442 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS107 | |
| J | LYS107 | |
| K | LYS107 | |
| L | LYS107 | |
| B | LYS107 | |
| C | LYS107 | |
| D | LYS107 | |
| E | LYS107 | |
| F | LYS107 | |
| G | LYS107 | |
| H | LYS107 | |
| I | LYS107 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| A | ASP280 | |
| A | ASN224 | |
| A | THR131 | |
| A | CYS276 | |
| A | LYS220 | |
| A | GLU165 |
| site_id | CSA10 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| J | ASP280 | |
| J | ASN224 | |
| J | THR131 | |
| J | CYS276 | |
| J | LYS220 | |
| J | GLU165 |
| site_id | CSA11 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| K | ASP280 | |
| K | ASN224 | |
| K | THR131 | |
| K | CYS276 | |
| K | LYS220 | |
| K | GLU165 |
| site_id | CSA12 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| L | ASP280 | |
| L | ASN224 | |
| L | THR131 | |
| L | CYS276 | |
| L | LYS220 | |
| L | GLU165 |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| B | ASP280 | |
| B | ASN224 | |
| B | THR131 | |
| B | CYS276 | |
| B | LYS220 | |
| B | GLU165 |
| site_id | CSA3 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| C | ASP280 | |
| C | ASN224 | |
| C | THR131 | |
| C | CYS276 | |
| C | LYS220 | |
| C | GLU165 |
| site_id | CSA4 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| D | ASP280 | |
| D | ASN224 | |
| D | THR131 | |
| D | CYS276 | |
| D | LYS220 | |
| D | GLU165 |
| site_id | CSA5 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| E | ASP280 | |
| E | ASN224 | |
| E | THR131 | |
| E | CYS276 | |
| E | LYS220 | |
| E | GLU165 |
| site_id | CSA6 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| F | ASP280 | |
| F | ASN224 | |
| F | THR131 | |
| F | CYS276 | |
| F | LYS220 | |
| F | GLU165 |
| site_id | CSA7 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| G | ASP280 | |
| G | ASN224 | |
| G | THR131 | |
| G | CYS276 | |
| G | LYS220 | |
| G | GLU165 |
| site_id | CSA8 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| H | ASP280 | |
| H | ASN224 | |
| H | THR131 | |
| H | CYS276 | |
| H | LYS220 | |
| H | GLU165 |
| site_id | CSA9 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1dli |
| Chain | Residue | Details |
| I | ASP280 | |
| I | ASN224 | |
| I | THR131 | |
| I | CYS276 | |
| I | LYS220 | |
| I | GLU165 |
