2Q2E

Crystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazei

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0003916	molecular_function	DNA topoisomerase activity
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005694	cellular_component	chromosome
A	0006259	biological_process	DNA metabolic process
A	0006265	biological_process	DNA topological change
A	0006268	biological_process	DNA unwinding involved in DNA replication
A	0046872	molecular_function	metal ion binding
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003916	molecular_function	DNA topoisomerase activity
B	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0006265	biological_process	DNA topological change
B	0006268	biological_process	DNA unwinding involved in DNA replication

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00322

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00132