2PQ5

Crystal structure of Dual specificity protein phosphatase 13 (DUSP13)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004722	molecular_function	protein serine/threonine phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006470	biological_process	protein dephosphorylation
A	0007283	biological_process	spermatogenesis
A	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
A	0016311	biological_process	dephosphorylation
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0033549	molecular_function	MAP kinase phosphatase activity
A	0043409	biological_process	negative regulation of MAPK cascade
A	0051321	biological_process	meiotic cell cycle
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004722	molecular_function	protein serine/threonine phosphatase activity
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006470	biological_process	protein dephosphorylation
B	0007283	biological_process	spermatogenesis
B	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
B	0016311	biological_process	dephosphorylation
B	0016787	molecular_function	hydrolase activity
B	0016791	molecular_function	phosphatase activity
B	0033549	molecular_function	MAP kinase phosphatase activity
B	0043409	biological_process	negative regulation of MAPK cascade
B	0051321	biological_process	meiotic cell cycle
C	0004721	molecular_function	phosphoprotein phosphatase activity
C	0004722	molecular_function	protein serine/threonine phosphatase activity
C	0004725	molecular_function	protein tyrosine phosphatase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006470	biological_process	protein dephosphorylation
C	0007283	biological_process	spermatogenesis
C	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
C	0016311	biological_process	dephosphorylation
C	0016787	molecular_function	hydrolase activity
C	0016791	molecular_function	phosphatase activity
C	0033549	molecular_function	MAP kinase phosphatase activity
C	0043409	biological_process	negative regulation of MAPK cascade
C	0051321	biological_process	meiotic cell cycle
D	0004721	molecular_function	phosphoprotein phosphatase activity
D	0004722	molecular_function	protein serine/threonine phosphatase activity
D	0004725	molecular_function	protein tyrosine phosphatase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006470	biological_process	protein dephosphorylation
D	0007283	biological_process	spermatogenesis
D	0008138	molecular_function	protein tyrosine/serine/threonine phosphatase activity
D	0016311	biological_process	dephosphorylation
D	0016787	molecular_function	hydrolase activity
D	0016791	molecular_function	phosphatase activity
D	0033549	molecular_function	MAP kinase phosphatase activity
D	0043409	biological_process	negative regulation of MAPK cascade
D	0051321	biological_process	meiotic cell cycle

Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCamGvsRSA

Chain	Residue	Details
A	VAL136-ALA146

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	296
Details	Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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