2PNZ
Crystal structure of the P. abyssi exosome RNase PH ring complexed with UDP and GMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| A | 0000177 | cellular_component | cytoplasmic exosome (RNase complex) |
| A | 0000178 | cellular_component | exosome (RNase complex) |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0016075 | biological_process | rRNA catabolic process |
| A | 0016896 | molecular_function | RNA exonuclease activity, producing 5'-phosphomonoesters |
| B | 0000177 | cellular_component | cytoplasmic exosome (RNase complex) |
| B | 0000178 | cellular_component | exosome (RNase complex) |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006401 | biological_process | RNA catabolic process |
| B | 0016075 | biological_process | rRNA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE UDP A 250 |
| Chain | Residue |
| A | MET81 |
| A | HOH285 |
| A | HOH346 |
| A | ARG97 |
| A | ASP133 |
| A | ALA134 |
| A | GLY135 |
| A | THR136 |
| A | ARG137 |
| A | ASP180 |
| A | ASP186 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 5GP A 279 |
| Chain | Residue |
| A | ARG89 |
| A | LYS91 |
| A | HOH318 |
| A | HOH377 |
| B | GLU69 |
| B | PHE71 |
| B | THR81 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 251 |
| Chain | Residue |
| A | ASP180 |
| A | GLY183 |
| A | ALA185 |
| A | ASP204 |
| A | HOH300 |
| B | GLU116 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 252 |
| Chain | Residue |
| A | TYR24 |
| A | LEU173 |
| A | LYS221 |
| A | ALA225 |
| A | HOH341 |
| B | LYS256 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 280 |
| Chain | Residue |
| B | GLU190 |
| B | ILE192 |
| B | GLU227 |
| B | HOH388 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD B 281 |
| Chain | Residue |
| B | PHE30 |
| B | ASN203 |
| B | LEU205 |
| B | TYR249 |
| B | HOH383 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 282 |
| Chain | Residue |
| A | ARG76 |
| A | ASP124 |
| A | PHE126 |
| B | PRO96 |
