Functional Information from GO Data
Chain | GOid | namespace | contents |
X | 0000165 | biological_process | MAPK cascade |
X | 0004672 | molecular_function | protein kinase activity |
X | 0004674 | molecular_function | protein serine/threonine kinase activity |
X | 0004708 | molecular_function | MAP kinase kinase activity |
X | 0005524 | molecular_function | ATP binding |
X | 0005634 | cellular_component | nucleus |
X | 0005737 | cellular_component | cytoplasm |
X | 0006468 | biological_process | protein phosphorylation |
X | 0016301 | molecular_function | kinase activity |
X | 0044773 | biological_process | mitotic DNA damage checkpoint signaling |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE K51 X 344 |
Chain | Residue |
X | LEU34 |
X | ASP123 |
X | SER176 |
X | LEU179 |
X | ASP190 |
X | HOH354 |
X | HOH387 |
X | ASN35 |
X | ALA53 |
X | LYS55 |
X | LEU101 |
X | TYR117 |
X | GLU118 |
X | TYR119 |
X | MET120 |
Functional Information from PROSITE/UniProt
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IcHrDVKpsNILM |
Chain | Residue | Details |
X | ILE168-MET180 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
X | ASP172 | |
X | SER176 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
X | ASP172 | |
X | LYS174 | |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
X | ASP172 | |
X | THR208 | |
X | LYS174 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ir3 |
Chain | Residue | Details |
X | ASP172 | |
X | ASN177 | |
X | LYS174 | |