2PJL
Crystal Structure of Human Estrogen-Related Receptor alpha in Complex with a Synthetic Inverse Agonist reveals its Novel Molecular Mechanism
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 047 A 600 |
| Chain | Residue |
| A | HOH5 |
| A | VAL321 |
| A | LEU324 |
| A | GLU331 |
| A | PHE382 |
| A | GLY397 |
| A | PHE495 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 047 B 700 |
| Chain | Residue |
| B | PHE328 |
| B | GLU331 |
| B | PHE382 |
| B | LEU386 |
| B | GLY397 |
| B | LEU398 |
| B | PHE495 |
| B | LEU500 |
| B | HOH11 |
| B | LEU324 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | ALA403 | |
| B | ALA403 |
